Solubility of hypericin in methanol and methanol-pyridine.

Pharmazie

Department of Applied BioSciences, Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology (ETH), Zürich, Switzerland.

Published: August 2002

The solubility of hypericin in methanol and methanol-pyridine (99:1, v/v) was determined. The addition of pyridine turned out to enhance the solubility of hypericin. In pure methanol only 37.17 micrograms/ml could be dissolved. In comparison, 320.91 micrograms hypericin were soluble in one ml methanol-pyridine (99:1, v/v).

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