An elaborated protocol is described which allows the efficient transformation of di-, tri-, and tetrapeptides into cyclopeptides with a minimum of protection and activation chemistry using the photoinduced electron transfer initiated decarboxylation of N-phthaloyl peptides resulting in C-C coupling between the initially formed carbon radicals.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/ja025804o | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Efficacy and Safety of Continuous vs Intermittent Linezolid Infusion in Critically Ill Patients with Septic Shock.
Indian J Crit Care Med
December 2024
Department of Anesthesia and ICU, Ain Shams University, Cairo, Egypt.
Unlabelled: The synthetic antimicrobial agent Linezolid effectively penetrates many tissues and exhibits effectiveness against drug-resistant Gram-positive bacteria. This agent's pharmacokinetic qualities cast doubt on the need for intravenous treatment in cases of serious illness. For its time-dependent action to have an impact, serum levels must stay above the minimum inhibitory concentration throughout the dosage interval.
View Article and Find Full Text PDFAssessment of HACCP plans and Colombian regulations in municipal cattle slaughterhouses for the assurance of standardised food safety and quality management systems.
Heliyon
December 2024
Departamento de Agroindustria, Facultad de Ciencias Agrarias, Universidad Del Cauca, Sede Las Guacas, A.A, 190002, Popayán, Colombia.
Colombia has strengthened regulations to ensure standardized food safety and quality in bovine slaughterhouses. To this end, the Ministry of Health and Social Protection designed to empower INVIMA, as the governing and coordinating authority for the operation of the Official Meat Inspection, Surveillance and Control System. This regulation aims to evaluate the technical conditions of infrastructures, slaughter processes and quality and safety assurance systems.
View Article and Find Full Text PDFConsensus findings of an International Workshops on Genotoxicity Testing workshop on using transcriptomic biomarkers to predict genotoxicity.
Environ Mol Mutagen
January 2025
Department of Biology, University of Ottawa, Ottawa, Ontario, Canada.
Gene expression biomarkers have the potential to identify genotoxic and non-genotoxic carcinogens, providing opportunities for integrated testing and reducing animal use. In August 2022, an International Workshops on Genotoxicity Testing (IWGT) workshop was held to critically review current methods to identify genotoxicants using transcriptomic profiling. Here, we summarize the findings of the workgroup on the state of the science regarding the use of transcriptomic biomarkers to identify genotoxic chemicals in vitro and in vivo.
View Article and Find Full Text PDFIncreasing microplastic concentrations have nonlinear impacts on the physiology of reef-building corals.
Sci Total Environ
January 2025
Department of Animal Ecology & Systematics, Justus Liebig University, Giessen, Germany; Hawai'i Institute of Marine Biology, University of Hawai'i at Mānoa, Kāne'ohe, HI, USA.
The pollution of marine environments with plastics, particularly microplastic (MP, i.e., plastic particles <5 mm), is a major threat to marine biota, including corals.
View Article and Find Full Text PDFAnalysis of the interaction mechanism between straw soil rotary tillage blade during rotary tillage process.
Sci Rep
January 2025
College of Mechanical and Electrical Engineering, Shihezi University, Shihezi, 832003, China.
In response to the rotary ploughing equipment in the stubble land to implement protective operations, the stubble is large in number and strong in toughness, not easy to crush, resulting in rotary ploughing equipment to produce entanglement and increased resistance to rotary ploughing and other issues. In this study, researchers designed a bionic rotary tillage blade (B-RTB) based on the bionic structural equations of the Marmota claw. A straw-soil complex shear performance test was conducted to investigate the effect of straw on soil shear strength.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!