Native mixed saliva of 86 children with congenital and acquired dentognathic system deformations and gastrointestinal tract diseases was investigated by specially devised method using optical reflecting microscope Neophot-2. In cytological preparations of mixed saliva all the cell elements were with signs of significant edema and cytolysis. In detritus different structures of lipid aggregations prevailed. The block of cellular immunity defense factors was detected. 3 grades of membrane destructive process caused by structure functional peculiarities of cytoplasmatic membranes organization were identified.
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