It has been suggested that estrogen supplementation can augment the treatment effects of typical antipsychotic medication. We report the use of estrogen supplementation for four female chronic inpatients. These patients were diagnosed with schizophrenia or schizoaffective disorders and were treated with atypical antipsychotics. Premenstrual exacerbation of psychiatric symptoms had been noted for all patients. Daily oral conjugated estrogen (Premarin 0.625 mg) was administered for three months continuously, and patients were assessed using the Nurses' Observation Scale for Inpatient Evaluation. Attenuation of premenstrual aggravation of psychiatric symptoms during menstruation was noted for two of the four cases, with substantial improvement noted for one of these. After Premarin treatment was discontinued, three patients were assessed as worse than the pre-supplementation phase using the evaluation scale. This finding is suggestive of individual variability for response to estrogen supplementation, with a possible association for onset age. Caution is advised where estrogen is used to treat schizophrenic patients taking atypical antipsychotics.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/s0163-8343(02)00193-7 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Effects of perinatal nutrition supplementation and early weaning on serum biochemistry, metabolomics, and reproduction in yaks.
Front Vet Sci
December 2024
Sichuan Academy of Grassland Sciences, Chengdu, China.
The transition period is a crucial stage in the reproductive cycle for dams and is linked closely with postpartum recovery, reproduction performance, and health. The confronting problem in the yak industry is that transition yaks under a conventional grazing feeding regime endure nutritional deficiency since this period is in late winter and early spring of the Qinghai-Tibet Plateau with the lack of grass on natural pasture. Therefore, this study aimed to investigate the effects of perinatal nutritional supplementation and early weaning on serum biochemistry, reproductive performance, and metabolomics in transition yaks.
View Article and Find Full Text PDFFSH/LH co-stimulation in Advanced Maternal Age (AMA) and hypo-responder patients - Arabian gulf delphi consensus group.
Front Endocrinol (Lausanne)
December 2024
The Fertility Clinic, Skive Regional Hospital, Skive, Department of Clinical Medicine, Aarhus University, Skive, Denmark.
Background: In a global effort to assess expert perspectives on the use of recombinant gonadotropins, recombinant human luteinizing hormone (r-hLH) and recombinant human follicle-stimulating hormone (r-hFSH), a consensus meeting was held in Dubai. The key aim was to address three critical questions: What are the factors that influence follicle response to gonadotropins? Which categories of patients are most likely to benefit from LH supplementation? And what are the optimal management strategies for these patients?
Methods: A panel of thirty-six experts reviewed and refined the initial statements and references proposed by the Scientific Coordinator. Consensus was defined as agreement or disagreement by more than two-thirds (66%) of the panel members for each statement.
Successful pregnancy and live birth despite discontinuation of hormone replacement therapy at 3 weeks and 5 days of gestation following vitrified-warmed embryo transfer under a hormone replacement therapy cycle: a case report and literature review.
BMC Pregnancy Childbirth
December 2024
Kameda IVF Clinic Makuhari, Makuhari, 261-8501, Japan.
Background: In freeze-thawed embryo transfer (FET) cycles, hormone replacement treatment (HRT) is crucial for implantation and pregnancy maintenance. HRT typically continues until the 10th week of pregnancy owing to a luteoplacental shift, although a definitive HRT regimen remains undetermined. We present the case of a woman who underwent FET during an HRT cycle and ceased HRT after a negative pregnancy test at 3 weeks and 5 days, who went on to deliver a healthy baby.
View Article and Find Full Text PDFSoybean isoflavone promotes milk yield and milk fat yield through the ERα-mediated Akt/mTOR pathway in dairy goats.
J Anim Sci
January 2024
Institute of Dairy Science, College of Animal Sciences, Zhejiang University, Hangzhou 310058, China.
Soybean isoflavone (SIF) in soybeans are natural phytoestrogens, which is functioned as an estrogen agonistic or antagonistic. SIF regulates the capacity of animals to synthesize triacylglycerols by directly utilizing long-chain fatty acids. However, few studies have focused on its regulatory lipid metabolism in lactating dairy goats.
View Article and Find Full Text PDFContraceptives or Hormone Replacement Therapy and Associations with Autoimmune Conditions: Exploring Effects of Estrogen Analog Supplementation.
ACR Open Rheumatol
December 2024
Jefferson Einstein Hospital, Philadelphia, Pennsylvania.
Objective: The aim of this study was to investigate the impact of estrogen and progesterone analog supplementation on the development of autoimmune conditions.
Methods: This retrospective observational study used data from the TriNetX network, which comprised over 100 million patients from 89 health care organizations. We compared patients exposed to estrogen and progesterone analogs to those exposed to progesterone-only therapy, using 1:1 propensity score matching based on age, ethnicity, and additional criteria.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!