The effects of SG schiff base complexes with Cu(II), Zn(II), Co(III) on O(2)(-). and DNA were studied. The results showed that both CuSG and ZnSG could an inhibit the synthesis of O(2)(-). markedly. The inhibiting effect of CuSG was larger than that of ZnSG. Complexes CuSG and CoSG could also combine with the salmon sperm DNA. The intrinsic association constant (K(0)) for CuSG and CoSG were estimated to be 2.86x10(4) M(-1 and 1.29x105) M-1 respectively. The numbers of binding sites per 100 nucleotide (n) were 2.5 and 7.5 respectively.
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