The objective of this cross-sectional study was to determine the mean period of school absenteeism (MPSA) among asthmatic Saudi schoolboys of Al-Khobar City and to determine the factors associated with the absenteeism. The methodology included the distribution of a self-administered questionnaire, which was completed by the parents of 1482 schoolboys who satisfied the selection criteria of the study. The prevalence rate of questionnaire-diagnosed asthma (QDA) was 9.5% (141/1482). The MPSA among questionnaire-diagnosed asthmatic boys (QDAs) was 13.6 +/- 3.4 days compared to 3.7 +/- 2.2 days among non questionnaire-diagnosed asthmatic boys (non QDAs). Among QDAs, the MPSA was associated significantly and positively with those who were younger, and with decreasing levels of socioeconomic class, histories of pets at home, presence of a currently smoking family member (father or both parents), visit to a hospital emergency room, and admission to hospital. It was significantly and negatively associated with concomitant use of prophylactic medication(s), including those used appropriately. The QDAs from middle and lower socioeconomic classes showed less use of prophylactic medication(s) but more histories of visits to an emergency room and of admissions to hospital. The multiple linear regression equation for the total period of school absenteeism (TPSA) during the 1995 academic year was generated. Asthmatic school children have a higher MPSA compared to their non asthmatic classmates. The risk of suffering the impacts of this disease is shown to be particularly increased among QDAs belonging to less socioeconomically advantaged families.
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http://dx.doi.org/10.1081/jas-120004034 | DOI Listing |
Healthcare (Basel)
December 2024
Department of Emergency, King Fahad Hospital of the University, Al-Khobar 34445, Eastern Province, Saudi Arabia.
Tranexamic acid (TXA) is a synthetic antifibrinolytic agent that inhibits plasminogen activation, thereby reducing bleeding. The aim of this systematic review was to investigate its role in aneurysmal subarachnoid hemorrhage (SAH)-a condition indicated by bleeding between two layers of brain tissue-to stop rebleeding and improve patient outcomes. We conducted a systematic review and meta-analysis of randomized controlled trials from 1981 to 2024, focusing on the efficacy and safety of TXA in treating aneurysmal SAH (PROSPERO registration: CRD42024504834).
View Article and Find Full Text PDFJ Exp Med
December 2024
Section of Paediatric Infectious Disease, Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, UK.
Multisystem inflammatory syndrome in children (MIS-C) is a rare condition following SARS-CoV-2 infection associated with intestinal manifestations. Genetic predisposition, including inborn errors of the OAS-RNAseL pathway, has been reported. We sequenced 154 MIS-C patients and utilized a novel statistical framework of gene burden analysis, "burdenMC," which identified an enrichment for rare predicted-deleterious variants in BTNL8 (OR = 4.
View Article and Find Full Text PDFSaudi J Gastroenterol
November 2024
Department of Pediatrics (Gastroenterology Unit), College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Background: Although the role of fungi in gut inflammation in IBD has been suggested, data are still limited in ulcerative colitis (UC). Our aim was to describe the gut fungal profile in a pediatric UC in Saudi Arabia.
Methods: Fecal samples from children with UC and control samples provided by healthy school children were collected.
Healthcare (Basel)
November 2024
Effat College of Engineering, Effat University, Jeddah 21478, Saudi Arabia.
Introduction: Clinical trials are crucial for advancing medical knowledge and improving healthcare outcomes. Despite an increase in research publications in Saudi Arabia, clinical trial productivity has lagged behind. Understanding the barriers to conducting clinical trials in Saudi Arabia is essential.
View Article and Find Full Text PDFJ Multidiscip Healthc
November 2024
Department of Cardiology, College of Medicine, Tanta University Hospital, Tanta, Egypt.
Purpose: COVID-19 is a new disease caused by the recently discovered SARS-CoV-2 virus. The COVID-19 disease manifests in several ways and it may affect various systems, including the gastrointestinal, musculoskeletal, neurological, cardiovascular, and pulmonary systems. Individuals who have ad-additional health conditions, such as cardiovascular disorders, are particularly more likely to experience illness and death.
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