The medical treatment of ulceration of the legs in areas with a subcutaneous plaque of calcinosis is often unsuccessful. The phlebologists then refer the patient to a surgeon. A patient aged 58 years, with a previous history of phlebitis, presented on two successive occasions with ulceration in the area of a large calcification in the lower third of the left leg. Cicatrization was obtained by a surgical treatment. Such surgery must be preceded by local and complete vascular assessment and by appropriate pre-operative care. It consists mainly of ablation of bone sequestration in order to obtain a suitable surface on which to apply thin skin graft in strips. It is often necessary to carry out an internal saphenous crossectomy as well to treat an associated venous insufficiency.
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Clin Microbiol Rev
January 2025
Centro de Investigación en Salud Pública, Facultad de Medicina Humana, Universidad de San Martín de Porres, Lima, Peru.
SUMMARYSporotrichosis is a subacute-to-chronic infection endemic to tropical and subtropical regions. It usually involves subcutaneous tissue but can occasionally cause extracutaneous infections, especially in hyperendemic areas. Extracutaneous infections are classified based on the anatomic location of the lesion and the route of infection (primary or multifocal).
View Article and Find Full Text PDFInt J Surg
December 2024
Department of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine.
Introduction: Nipple-sparing mastectomy (NSM) aims to improve patient satisfaction by preserving the nipple-areola complex (NAC) while ensuring oncologic safety. Different surgical incisions, such as inframammary fold (IMF) and periareolar/radial incisions, are used in NSM; however, their impact on NAC sensory loss remains unclear. In this study, the authors aimed to assess NAC sensation after NSM and compare the results of different incisional approaches, specifically IMF versus periareolar/radial.
View Article and Find Full Text PDFEur J Public Health
January 2025
World Health Organization, Headquarters, Geneva, Switzerland.
Crimean-Congo hemorrhagic fever (CCHF) is an acute tick-borne disease with a case fatality rate of up to 40% in humans, posing a significant health threat. This study investigates the 2022-23 CCHF outbreaks in Iraq, the highest recorded to date, and analyzes potential factors at the human-animal-environmental interface. Data from the Iraqi government, the World Health Organization, and the World Bank were used to analyze CCHF trends and affecting factors.
View Article and Find Full Text PDFFolia Histochem Cytobiol
January 2025
Department of Colorectal Surgery, Hangzhou Red Cross Hospital, Hangzhou, China.
Introduction: Hepatocellular carcinoma (HCC) is the sixth most common type of cancer and the second leading cause of cancer death worldwide [19]. Opioid growth factor (OGF) has been shown to exhibit antitumour potential, binding to OGF receptor (OGFr). Naltrexone (NTX), an OGFr antagonist, is considered as a potential anti-cancer agent.
View Article and Find Full Text PDFJ Craniofac Surg
January 2025
State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University.
Lipomas are benign soft tissue tumors composed of mature adipocytes, commonly found in subcutaneous tissues. Despite their prevalence in various body regions, they are relatively rare in the oral and maxillofacial regions. This study retrospectively analyzed the clinical and imaging characteristics, as well as the treatment outcomes of 57 patients diagnosed with lipoma.
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