To assess the suitability of the i-STAT portable analyser for use by non-laboratory personnel, we measured blood gases and pH in venous blood samples from 100 dogs. Deming's regression and bias plots were used to compare i-STAT results with those obtained by laboratory professionals using two different autocalibrated benchtop analysers. Overall accuracy of the portable analyser proved excellent for pH, pO(2), and pCO(2) (r=0.978, 0.968 and 0.997, respectively), with Deming's regression slopes close to 1.00 (0.96, 0.97 and 1.08 for pH, pO(2), and pCO(2), respectively) and intercepts close to zero (0.28, 0.47 kPa and 0.46 kPa for pH, pO(2), and pCO(2), respectively). The accuracy of the i-STAT was also satisfactory for calculated parameters: bicarbonates, total CO(2), base excess and oxygen saturation. Our findings show this portable analyser to be a valid substitute for expensive benchtop analysers in situations requiring mobility, or when small numbers of tests are to be performed by users not specialized in laboratory techniques.
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http://dx.doi.org/10.1016/s0034-5288(02)00065-6 | DOI Listing |
Asian J Transfus Sci
August 2024
Department of Transfusion Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Introduction: Hemoglobin (Hb) estimation in blood donors is conducted using capillary samples on portable hemoglobinometers, representing measurement methods in practice. The reference standard is conducted using a venous sample on a hematology analyzer, representing the mentor measurement method or the true value. The correction involves the calculation of the secondary adjustment factor (SAF) to mitigate the difference between the two values.
View Article and Find Full Text PDFSensors (Basel)
January 2025
Department of Computer Science, Faculty of Sciences and Humanities Sciences, Majmaah University, Al Majmaah 11952, Saudi Arabia.
Impedance-based biosensing has emerged as a critical technology for high-sensitivity biomolecular detection, yet traditional approaches often rely on bulky, costly impedance analyzers, limiting their portability and usability in point-of-care applications. Addressing these limitations, this paper proposes an advanced biosensing system integrating a Silicon Nanowire Field-Effect Transistor (SiNW-FET) biosensor with a high-gain amplification circuit and a 1D Convolutional Neural Network (CNN) implemented on FPGA hardware. This attempt combines SiNW-FET biosensing technology with FPGA-implemented deep learning noise reduction, creating a compact system capable of real-time viral detection with minimal computational latency.
View Article and Find Full Text PDFPlant Physiol Biochem
January 2025
School of Life Sciences, Anhui Agricultural University, Hefei 230036, China; Engineering Research Center of Environmentally-friendly and Efficient Fertilizer and Pesticide of Anhui Province, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, China. Electronic address:
A deep understanding of ammonia (NH) emissions from cropland can promote efficient crop production. To date, little is known about leaf NH emissions because of the lack of rapid detection methods. We developed a method for detecting leaf NH emissions based on portable NH sensors.
View Article and Find Full Text PDFToxics
November 2024
Research Center for Environmental Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Growing concerns about the health risks of melamine adulteration in food products highlight the urgent need for reliable detection methods. However, the long-term effects of chronic low-level melamine exposure remain inadequately explored. This study introduces THE ONE InstantCare platform, a portable immunoassay analyzer integrating a SpectroChip-based spectral processing unit (SPU) with lateral flow immunoassay (LFIA) for sensitive and accurate quantification of melamine in human urine.
View Article and Find Full Text PDFAnal Methods
January 2025
Lead Exposure Elimination Project, London, W10 4BP, UK.
Determining lead (Pb) concentrations in new paints using spectroscopic methods such as Inductively Coupled Plasma-Optical Emission Spectroscopy (ICP-OES) requires technical expertise, consumables, equipment for method preparation, and instrumentation that can be cost prohibitive and difficult to maintain in low and middle-income countries (LMICs). Although portable X-ray Fluorescence (pXRF) analyzers are less expensive and simple to operate, their inaccuracy has limited their use to screening for the analysis of Pb in new, dried paint. To determine the limits of pXRF analyzers, new paint samples were purchased, dried, homogenized, and analyzed pXRF and ICP-OES.
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