The sequential simplex strategy has been used to optimize the mobile phase used for separation of inorganic anions by micellar chromatography on a C(18)- micro Bondapak column, with absorption detection at 230 nm. The amount of acetonitrile and the concentration of phosphate buffer (pH 6.0) were chosen for optimization. The optimum mobile phase was found to be 38% acetonitrile in 18.2 mmol L(-1) phosphate buffer (pH 6.0) containing 10 mmol L(-1) cetyltrimethylammonium bromide (CTAB); this optimum was achieved within seven experiments. The separation of the five anions (nitrite, nitrate, iodide, thiocyanate, and thiosulfate) was accomplished in 18 min.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s00216-002-1396-6 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Collateral damage: the overlooked reproductive health crisis in conflict zones.
Reprod Health
December 2024
The George Institute for Global Health, Imperial College London, London, UK.
Conflict-affected regions face severe reproductive health challenges that disproportionately impact adolescent girls and young women (AGYW) and children, who are especially vulnerable due to the breakdown of healthcare systems and limited access to essential services. AGYW are at heightened risk due to restricted access to family planning, prenatal care, and emergency obstetric services, while children face malnutrition, disease outbreaks, and developmental delays. These challenges have profound long-term consequences for both their physical and psychological well-being.
View Article and Find Full Text PDFA randomised controlled pilot trial protocol for patient led cognitive gamified training during haemodialysis.
Sci Rep
December 2024
University of York, York, England, UK.
Disruptions in cognitive function have been reported in individuals undergoing haemodialysis and those with chronic kidney disease. This pilot study protocol primarily assesses the feasibility and acceptability of using mobile cognitive gaming apps for patient-led cognitive training during haemodialysis sessions. The protocol consists of three phases: (1) reviewing and evaluating available cognitive gaming apps, (2) conducting focus groups/interviews with people with kidney disease to determine app preferences, and (3) undertaking a quasi-experimental randomised controlled trial to compare cognitive outcomes between a patient-led app intervention group and a standard care control group over four months.
View Article and Find Full Text PDFDevelopment of a Tablet-Based Outpatient Care Application for People With Dementia: Interview and Workshop Study.
JMIR Hum Factors
December 2024
Institute of Medical Sociology and Rehabilitation Science, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Charitéplatz 1, Berlin, 10117, Germany, 49 30-450576364.
Background: Dementia management presents a significant challenge for individuals affected by dementia, as well as their families, caregivers, and health care providers. Digital applications may support those living with dementia; however only a few dementia-friendly applications exist.
Objective: This paper emphasizes the necessity of considering multiple perspectives to ensure the high-quality development of supportive health care applications.
Influence of calcium carbonate on ferrihydrite bio-transformation and associated arsenic mobilization/redistribution.
Environ Pollut
December 2024
State Environmental Protection Key Laboratory of Integrated Surface Water-Groundwater Pollution Control, School of Environmental Science and Engineering, Southern University of Science and Technology, Shenzhen 518055, China.
The sulfate-reducing bacteria (SRB)-induced ferrihydrite transformation is an important cause for arsenic (As) contamination in the aquifer near mining area. Calcium carbonate (CaCO) is widespread and has the potential of regulating As fate directly or indirectly. However, the influence of CaCO on ferrihydrite transformation and the associated As mobilization/redistribution in SRB-containing environments remains unclear.
View Article and Find Full Text PDFChromatographic Separation and Quantification of Nine Nitrosamine Genotoxic Impurities in a Single Method in Nebivolol Tablet by Using Validated Ultra-Sensitive Liquid Chromatography: Mass Spectrometry Analytical Method.
J Chromatogr Sci
December 2024
Analytical Research Laboratory, Cadila Pharmaceuticals Ltd., Dholka, Ahmedabad 382225, India.
N-nitrosamine impurities have been detected in a vast variety of drug substances and drug products, showing concern for regulatory aspects. To meet the regulatory requirement for the concerned impurity, a sensitive analytical method capable of quantifying these impurities at a lower level with accuracy and precision is required. This article focuses on the development and validation of an analytical method for the simultaneous detection of nine nitrosamine impurities in a single method for nebivolol drug product using liquid chromatography-mass spectrometry/mass spectrometry-atmospheric pressure chemical ionization (LC-MS/MS-APCI).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!