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Performance of two commercial glycoprotein G-based enzyme immunoassays for detecting antibodies to herpes simplex viruses 1 and 2 in children and young adolescents. | LitMetric
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Performance of two commercial glycoprotein G-based enzyme immunoassays for detecting antibodies to herpes simplex viruses 1 and 2 in children and young adolescents.

Charles T Leach Rhoda L Ashley Jacques Baillargeon Hal B Jenson

Clin Diagn Lab Immunol

Department of Pediatrics, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229-3900, USA.

Published: September 2002

In 61 patients 1 to 14 years of age, the Gull/Meridian enzyme-linked immunosorbent assay (ELISA) had a sensitivity of 100% for herpes simplex virus type 1 (HSV-1) and specificities of 74% for HSV-1 and 48% for HSV-2. In 128 similarly aged patients, the HerpeSelect ELISA (Focus Technologies) showed sensitivities of 80% for HSV-1 and 88% for HSV-2, and specificities of 97% for HSV-1 and 100% for HSV-2.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC120053PMC
http://dx.doi.org/10.1128/cdli.9.5.1124-1125.2002DOI Listing

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