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Oral streptococci and induce distinct morphological, inflammatory, and metabolic signatures in macrophages.
Infect Immun
March 2024
Department of Immunobiology, College of Medicine, The University of Arizona, Tucson, Arizona, USA.
Oral streptococci, key players in oral biofilm formation, are implicated in oral dysbiosis and various clinical conditions, including dental caries, gingivitis, periodontal disease, and oral cancer. Specifically, is associated with esophageal, gastric, and pharyngeal cancers, while is linked to oral cancer. However, no study has investigated the mechanistic links between these species and cancer-related inflammatory responses.
View Article and Find Full Text PDFNovel Case of Streptococcus Mitis-infected Chronic Subdural Hematoma.
Acta Neurol Taiwan
September 2024
Department of Neurosurgery, University of New Mexico Hospital, Albuquerque, New Mexico, USA.
Purpose: Subdural hematoma (SDH) is a common pathology found in neurosurgery. Infected SDH, however, is less common, and reports have typically identified Escherichia coli as the causative organism.
Case Report: We present here a case of an infected chronic SDH caused by Streptococcus mitis, likely for the first time, following a burn injury in a 40-year-old male patient.
Pathogenic bacterial species associated with endodontic infection evade innate immune control by disabling neutrophils.
Infect Immun
October 2014
Department of Immunology and Infectious Diseases, The Forsyth Institute, Cambridge, Massachusetts, USA Harvard School of Dental Medicine, Boston, Massachusetts, USA
Endodontic infections, in which oral bacteria access the tooth pulp chamber, are common and do not resolve once established. To investigate the effects of these infections on the innate immune response, we established a mouse subcutaneous chamber model, where a mixture of four oral pathogens commonly associated with these infections (endodontic pathogens [EP]), i.e.
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