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http://dx.doi.org/10.1002/1521-3773(20020802)41:15<2753::AID-ANIE2753>3.0.CO;2-M | DOI Listing |
Org Lett
October 2016
Department of Chemistry, Oklahoma State University, 107 Physical Sciences 1, Stillwater, Oklahoma 74078, United States.
α,β-Unsaturated amides are important building blocks and are key structural elements in a number of biologically active natural products. Despite their importance and prevalence, few methods exist to prepare conjugated amides directly and modularly. To address this gap, a titanium-promoted coupling of alkynes and isocyanates has been developed.
View Article and Find Full Text PDFOrg Lett
June 2008
Laboratory of Modern Synthetic Organic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China.
We have developed novel asymmetric routes to (-)-9- epi-pentazocine and (-)-aphanorphine from a d-tyrosine derivative. The tricyclic frameworks of (-)-9- epi-pentazocine and (-)-aphanorphine were assembled stereoselectively via intramolecular Friedel-Crafts reaction of the corresponding bicyclic precursors, generated with titanium-promoted enyne cyclization and indium-initiated atom-transfer radical cyclization, respectively.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
August 2002
Departamento de Química Orgánica (C-I), Universidad Autónoma Cantoblanco, 28049 Madrid, Spain.
J Org Chem
January 1997
Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, Florida 32611-7200.
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