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Detection of chromosome aberrations in 17 054 individuals with fertility problems and their subsequent assisted reproductive technology treatments in Central China.
Hum Reprod
November 2023
Reproductive Medicine Center, Tongji Hospital, Tongji Medicine College, Huazhong University of Science and Technology, Wuhan, People's Republic of China.
Article Synopsis
- In a study of 17,054 infertile couples in central China, researchers found that chromosome aberrations significantly impact male fertility and ART outcomes, with men showing a higher incidence of semen quality issues.
- Couples with reciprocal translocations had notably lower pregnancy rates compared to those with other types of chromosome abnormalities.
- Despite the findings, the existing data on how different chromosome types affect sperm quality and ART success rates remain limited and somewhat contentious.
Meiotic Chromosomal Abnormality Detected in a Heterozygote of .
Front Plant Sci
May 2022
Key Laboratory of Adaptation and Evolution of Plateau Biota, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining, China.
is an allopolyploid with a genome constitution of StStYYHH (2 = 6 = 42). Highly frequent intergenomic translocations and chromosomal variations with repeat amplification and deletions in have been identified in the previous studies. However, more complicated structural variations such as chromosomal inversions or intra-genomic translocations are still unknown in this species, so does the reason for the origin of the chromosomal variations.
View Article and Find Full Text PDFPredominant wheat-alien chromosome translocations in newly developed wheat of China.
Mol Breed
April 2021
State Key Laboratory of Crop Genetics and Germplasm Enhancement, Nanjing Agricultural University, Nanjing, 210095 China.
Unlabelled: Founder wheat lines have played key role in Chinese wheat improvement. Wheat- translocation T6VS·6AL has been widely used in wheat breeding in recent years due to its high level of powdery mildew resistance and other beneficial genes. Reference oligo-nucleotide multiplex probe (ONMP)-FISH karyotypes of six T6VS·6AL donor lines were developed and used for characterizing 32 derivative cultivars and lines.
View Article and Find Full Text PDFChicken embryonic stem cells and primordial germ cells display different heterochromatic histone marks than their mammalian counterparts.
Epigenetics Chromatin
February 2016
Inserm, U1208, INRA, USC1361, Stem Cell and Brain Research Institute, 18 avenue du Doyen Lépine, 69500 Bron, France ; Université de Lyon, Université Lyon 1, Lyon, France.
Background: Chromatin epigenetics participate in control of gene expression during metazoan development. DNA methylation and post-translational modifications (PTMs) of histones have been extensively characterised in cell types present in, or derived from, mouse embryos. In embryonic stem cells (ESCs) derived from blastocysts, factors involved in deposition of epigenetic marks regulate properties related to self-renewal and pluripotency.
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