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Molecular epidemiology of invasive group B Streptococcus in South Africa, 2019-2020.
J Infect Dis
December 2024
Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases, a division of the National Health Laboratory Service, Johannesburg, South Africa.
Background: Group B Streptococcus (GBS) is a leading cause of neonatal meningitis and sepsis and an important cause of disease in adults. Capsular polysaccharide and protein-based GBS vaccines are currently under development.
Methods: Through national laboratory-based surveillance, invasive GBS isolates were collected from patients of all ages between 2019 and 2020.
Molecular characterization and antimicrobial susceptibility for 62 isolates of from children.
Front Microbiol
December 2024
Hebei Key Laboratory of Pathogens and Epidemiology of Infectious Diseases, HeBei Provincial Center for Disease Control and Prevention, Shijiazhuang, China.
Background: Pertussis is a highly contagious respiratory disease caused by (BP). Despite global control of pertussis cases through the Expanded Programme on Immunization (EPI), there has been a significant increase in the incidence of pertussis in recent years, characterized by a "resurgence" in developed countries with high immunization rates as well as a comparable reemergence in certain areas of China. We aim to explore the genotypes and antimicrobial susceptibility of circulating BP from children in Hebei.
View Article and Find Full Text PDFExpert consensus for pertussis in children: new concepts in diagnosis and treatment.
World J Pediatr
December 2024
Department of Infectious Diseases, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, 310052, China.
Background: Pertussis resurgence has been reported worldwide in the past two decades. Pertussis is still endemic and difficult to control though with universal vaccination in children. The resurgence may be related to multiple variables, such as increased disease awareness and laboratory tests, waning of immunity following vaccination, and/or genetic mutations of Bordetella pertussis.
View Article and Find Full Text PDFCharacterization of group A streptococci causing invasive diseases in Sri Lanka.
Access Microbiol
June 2024
Department of Microbiology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, SAR.
Article Synopsis
- Group A β haemolytic streptococcus (GAS) is a pathogen that causes various infections in humans, and this study analyzed 51 GAS isolates from invasive infections in Sri Lanka.
- The isolates were tested for resistance to antibiotics like erythromycin and tetracycline, revealing that all were susceptible to penicillin and showing diverse patterns of resistance and virulence markers.
- Key findings included a 70.6% non-susceptibility rate to tetracycline and the detection of significant virulence markers, indicating a varied genetic background among the isolates.
Heat stress enhances the occurrence of erythromycin resistance of Enterococcus isolates in mice feces.
J Therm Biol
February 2024
Fujian Key Laboratory of Traditional Chinese Veterinary Medicine and Animal Health, College of Animal Sciences (College of Bee Science), Fujian Agriculture and Forestry University, Fuzhou, 350002, China. Electronic address:
Heat stress is a common environmental factor in livestock breeding that has been shown to impact the development of antibiotic resistance within the gut microbiota of both human and animals. However, studies investigating the effect of temperature on antibiotic resistance in Enterococcus isolates remain limited. In this study, specific pathogen free (SPF) mice were divided into a control group maintained at normal temperature and an experimental group subjected to daily 1-h heat stress at 38 °C, respectively.
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