A novel approach to solving microdosimetry problems using conditional probabilities and geometric concepts has been developed. This approach is valid for cases where a convex site is immersed in uniform or discontinuous distributions of heavy charged particle tracks and assumes no restrictions in site geometry or the kind of randomness. These conditions are relevant to the study of microdosimetry in applications such as neutron capture therapy (NCT), irradiation experiments using heavy ion particle beams, environmental radon, or occupational exposure to radioactive materials. Expressions applicable to the case of surface-distributed sources of tracks are presented that may represent situations such as NCT, where boron compounds are bound to the membranes of cellular nuclei. Microdosimetric spectra, specific energy averages, and mean number of 10B capture reactions for cell inactivation are calculated, showing their dependence on 10B localisation.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1093/oxfordjournals.rpd.a006825 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A head-to-head comparison of the adult EQ-5D-5L and youth EQ-5D-Y-5L in adolescents with idiopathic scoliosis.
J Patient Rep Outcomes
January 2025
EuroQol Research Foundation, Rotterdam, The Netherlands.
Background: Multiple diseases, such as Adolescent Idiopathic Scoliosis (AIS), present at adolescent age and the impact on quality of life (QoL) prolongs into adulthood. For the EQ-5D, a commonly used instrument to measure QoL, the current guideline is ambiguous whether the youth or adult version is to be preferred at adolescent age. To assess which is most suitable, this study tested for equivalence along predefined criteria of the youth (EQ-5D-5L) and adult (EQ-5D-Y-5L) version in an adolescent population receiving bracing therapy for AIS.
View Article and Find Full Text PDFExploration of the genetic landscape of bacterial dsDNA viruses reveals an ANI gap amid extensive mosaicism.
mSystems
January 2025
Malopolska Centre of Biotechnology, Jagiellonian University, Kraków, Poland.
Average nucleotide identity (ANI) is a widely used metric to estimate genetic relatedness, especially in microbial species delineation. While ANI calculation has been well optimized for bacteria and closely related viral genomes, accurate estimation of ANI below 80%, particularly in large reference data sets, has been challenging due to a lack of accurate and scalable methods. To bridge this gap, we introduce MANIAC, an efficient computational pipeline optimized for estimating ANI and alignment fraction (AF) in viral genomes with divergence around ANI of 70%.
View Article and Find Full Text PDFIn this paper, we introduce a new method for precise determination of the calibration function of liquid crystal spatial light modulators (LC-SLMs). The proposed method shares the advantages of commonly used methods, interferometric and diffraction-based methods, and is free of their disadvantages. The method proposed here is based on the evaluation of Fresnel diffraction of light from a phase-discontinuity pattern loaded into the SLM device.
View Article and Find Full Text PDFBias in Discontinuous Elevational Transects for Tracking Species Range Shifts.
Plants (Basel)
January 2025
College of Life Sciences, Zhejiang University, Hangzhou 310058, China.
Climate change is compelling species to seek refuge at higher elevations and latitudes. While researchers commonly study these migrations using discontinuous elevational transects, this methodology may introduce significant biases into our understanding of species movement. These potential biases could lead to flawed biodiversity conservation policies if left unexamined.
View Article and Find Full Text PDFInfluence of the Thermoplastic Fiber Ratio on the Mechanical Properties of Recycled Carbon Fibers During the Carding Process.
Materials (Basel)
January 2025
ULR 2461-GEMTEX-Génie et Matériaux Textiles-Gemtex, Ensait, University of Lille, F-59000 Lille, France.
This study investigates the impact of carding and blending recycled carbon fibers (rCF) with crimped thermoplastic polypropylene (PP) fibers on the mechanical properties of rCF, using a Weibull statistical approach. Tensile properties of rCF were evaluated before and after carding with varying rCF/PP blend ratios (100/0%, 85/15%, 70/30%, and 50/50%). A comparison between the two-parameter and three-parameter Weibull models showed that the two-parameter model provided a better fit for rCF properties before carding.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!