The influence of acute and chronic gamma irradiation (0.25 and 0.5 Gy doses) on rat lymphocytes was examined on the 1st and 10th days after irradiation. Acute gamma irradiation increased the intracellular calcium concentration in the cytoplasm of the lymphocytes on the 1st day after the influence of the radiation. Calcium concentration returned to the control level on the 10th day after the effect of the radiation at all the doses. In the lymphocytes after acute irradiation the increase of the Ca2+ concentration in the intracellular depots on the 1st day was observed. Changes were also observed in the physicochemical state of the plasma membrane of these cells. Research on the influence of prolonged gamma irradiation on intracellular calcium homeostasis revealed opposite effects in comparison with acute gamma irradiation.
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| http://dx.doi.org/10.1093/oxfordjournals.rpd.a006755 | DOI Listing |
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