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Bioorthogonal click chemistry and aptamer-targeting enables highly selective fluorescence labeling of exosomal glycosylated EpCAM for super resolved imaging.
Anal Chim Acta
February 2025
School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, 100081, PR China. Electronic address:
Exosomes, which are known to transport diverse proteins from parent cells to recipient cells, consequently influence the biological activities of the recipient cells. Among those proteins, the epithelial cell adhesion molecule (EpCAM), plays a crucial role as it is implicated in cell adhesion and signaling processes. As exosomal EpCAM potentially affects the migration of recipient cells, direct visualization with high spatial resolution is essential to better understand this impact and the role of exosomal EpCAM in recipient cells.
View Article and Find Full Text PDFBackground & Aims: This systematic literature review of qualitative findings aims to identify the perceived barriers and enablers for hepatocellular carcinoma (HCC) surveillance from patient and clinician perspectives.
Methods: A systematic search of databases using key term combinations with the following inclusion criteria: 1) qualitative and quantitative (survey) studies exploring barriers and enablers of HCC surveillance, and 2) qualitative and quantitative (survey) studies exploring barriers and enablers of enagagement in clinical care for patients with cirrhosis and/or viral hepatitis.
Results: The search returned 445 citations: 371 did not meet the study criteria and were excluded.
Women decision-making on modern contraceptive use and its associated factors among married women in Girawa District, Eastern Ethiopia: a community-based cross-sectional study, 2024.
BMC Public Health
December 2024
College of Health and Medical Science, School of Nursing and Midwifery, Haramaya University, Harar, Ethiopia.
Background: Women's decision-making power on contraceptive use is crucial for increasing modern contraceptive uptake. However, evidence in Ethiopia regarding this topic is limited and inconclusive.
Objective: To assess the prevalence and factors associated with women's decision-making power on modern contraceptive use in Girawa district, Eastern Ethiopia, January 1-30, 2024.
Understanding the experiences and needs of assistive technology users in Queensland.
Disabil Rehabil Assist Technol
December 2024
School of Allied Health Sciences and Practice, University of Adelaide, South Australia, Australia.
Assistive technology (AT) can significantly enhance the daily lives of people with disabilities if matched appropriately to the individual and their context. Gaps remain in the AT sector in terms of provision and uptake. Consequently, this study examined current experiences and needs regarding AT provision throughout Queensland from AT users' perspectives.
View Article and Find Full Text PDFMulticomponent Workplace Tobacco Cessation Interventions: A Scoping Review.
Workplace Health Saf
January 2025
Alberta Health Services.
Introduction: Tobacco is the leading modifiable risk factor for cancer and other chronic diseases. The workplace provides an opportunity to advance tobacco cessation efforts. Combining tobacco cessation with complementary components addressing mental health, physical activity, and healthy eating has demonstrated effectiveness in non-workplace settings.
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