Mass spectrometry: an emerging alternative to traditional methods for measurement of diagnostic proteins, peptides and amino acids.

Curr Protein Pept Sci

Central Research, Cargill, Inc., PO Box 5702, Minneapolis, MN 55440-5702, USA.

Published: April 2002

AI Article Synopsis

  • Novel mass spectrometry techniques are being developed to improve protein measurement, offering alternatives to traditional methods.
  • The review highlights the use of mass spectrometry for analyzing key proteins and compounds like transferrin, transthyretin, glycated hemoglobin, and homocysteine in clinical settings.
  • It also addresses the limitations of mass spectrometry and discusses potential future developments in clinical protein measurement.

Article Abstract

Novel approaches to protein measurement based on mass spectrometry are being developed that challenge more traditional methods. This review summarizes the emergence of mass spectrometry as a tool for clinical protein, peptide, and amino acid determination. Specific applications of mass spectrometry to the measurement of transferrin, transthyretin, glycated hemoglobin, and homocysteine will be discussed, as will the limitations of the technology, and future directions for clinical protein measurement.

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http://dx.doi.org/10.2174/1389203024605377DOI Listing

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