Anticipatory evolution and DNA shuffling.

Genome Biol

Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX 78712, USA.

Published: July 2002

DNA shuffling has proven to be a powerful technique for the directed evolution of proteins. A mix of theoretical and applied research has now provided insights into how recombination can be guided to more efficiently generate proteins and even organisms with altered functions.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC139397PMC
http://dx.doi.org/10.1186/gb-2002-3-8-reviews1021DOI Listing

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