DNA shuffling has proven to be a powerful technique for the directed evolution of proteins. A mix of theoretical and applied research has now provided insights into how recombination can be guided to more efficiently generate proteins and even organisms with altered functions.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC139397 | PMC |
http://dx.doi.org/10.1186/gb-2002-3-8-reviews1021 | DOI Listing |
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