Treatment of asymptomatic hyperuricemia is not necessary in most patients, unless perhaps they have very high levels of uric acid or are otherwise at risk of complications, such as those with a personal or strong family history of gout, urolithiasis, or uric acid nephropathy.
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http://dx.doi.org/10.3949/ccjm.69.8.594 | DOI Listing |
Trials
January 2025
Department of Traditional Chinese Medicine, The Eighth Affiliated Hospital, Sun Yat-Sen University, Shenzhen, 518033, Guangdong, P. R. China.
Background: The aim of this study is to evaluate the efficacy and safety of diacylglycerol (DAG) edible oil intervention in patients with chronic metabolic syndrome complicated by asymptomatic hyperuricemia through a multicenter, prospective, double-blind, randomized controlled clinical trial.
Methods: A multicenter, double-blind, and randomized controlled trial involving 176 patients was designed. All patients with chronic metabolic syndrome complicated by asymptomatic hyperuricemia who meet inclusion and exclusion criteria will be included in the study and will be randomized to either group A or group B.
Int J Rheum Dis
December 2024
Department of Ultrasound, The First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan, China.
Objective: To use ultrasound technology to assess the deposition of urate crystals in the common lower limb tendons of patients with gout, providing additional imaging information for the management of these patients.
Methods: High-frequency ultrasound was retrospectively used to evaluate urate crystal deposition in common lower limb tendons-quadriceps, patellar, and Achilles-in patients with gouty arthritis. Comparative statistical analysis was conducted among asymptomatic hyperuricemia patients and healthy individuals during the same period.
Nutr Metab Cardiovasc Dis
November 2024
Cardiology- Heart Failure and Transplants, Cardiotoracovascular Department "A. De Gasperis", Milan, Italy; Associazione Nazionale Medici Cardiologi Ospedalieri (ANMCO), Florence, Italy.
Aims: The most frequent consequence of elevated uric acid (UA) levels is the development of gout and urate kidney disease. Besides these effects, several studies have investigated the association between hyperuricemia and cardiovascular (CV) disease. High serum UA has been identified as an important determinant of all-cause and CV mortality and CV events (acute and chronic coronary syndrome, stroke and peripheral artery disease).
View Article and Find Full Text PDFBackground: Chronic kidney disease (CKD) is common in the German adult population, with a prevalence of 10%. This guideline, updated on the basis of current scientific evidence, contains recommendations for the management of CKD in general practice.
Methods: The updated guideline is based on a review and assessment of source guidelines and systematic reviews concerning individual questions.
Int J Womens Health
December 2024
Department of Obstetrics and Gynecology, Zhongda Hospital, Nanjing, Jiangsu, People's Republic of China.
Background: The impact of androgens on metabolic diseases, cardiovascular diseases (CVD), and long-term mortality in the general female population remains poorly understood. This study, utilizing data from the National Health and Nutrition Examination Survey (NHANES) database managed by the Centers for Disease Control and Prevention, seeks to elucidate the relationship between androgen levels and metabolic syndrome (MS), CVD, and mortality in adult women.
Methods: After excluding ineligible individuals, descriptive analyses were conducted on demographic characteristics, metabolic-related indicators, and disease prevalence, based on the presence of high androgenemia and androgen quartile grouping.
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