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Acute Febrile Illness Accompanied by 7th and 12th Cranial Nerve Palsy Due to Lyme Disease Following Travel to Rural Ecuador: A Case Report and Mini-Review.
Trop Med Infect Dis
January 2025
Division of Infectious Diseases, Department of Medicine, University of Toronto, Toronto, ON M5S 3H2, Canada.
The causative agent of Lyme disease, , is endemic to Canada, the northeastern United States, northern California, and temperate European regions. It is rarely associated with a travel-related exposure. In this report, we describe a resident of southern Ontario, Canada who developed rash, fever, and cranial nerve VII and XII palsies following a 12 day trip to Ecuador and the Galapagos islands approximately four weeks prior to referral to our center.
View Article and Find Full Text PDFConsolidated Newborn Bloodspot Screening Efforts in Developing Countries in the Asia Pacific-2024.
Int J Neonatal Screen
December 2024
Independent Researcher, 307-N, Street 113, Phase 1, DHA, Lahore 54792, Pakistan.
Approximately half of all births globally occur in the Asia Pacific Region. Concerted efforts to support local activities aimed at developing national newborn screening (NBS) have been ongoing for almost 30 years, first by the International Atomic Energy Agency (IAEA) and then through volunteer efforts. Sustainable newborn bloodspot screening (NBS) continues to be initiated and develop in many of the countries with developing economies in the region.
View Article and Find Full Text PDFBilateral chylothorax following total thyroidectomy with neck lymph node dissection for thyroid cancer: a case report and literature review.
Front Oncol
January 2025
Department of Head and Neck Surgery, Gansu Provincial Cancer Hospital, Lanzhou, China.
Purpose: Investigating the diagnosis and treatment of bilateral Chylothorax after neck lymph node dissection for thyroid cancer.
Methods: The clinical data of a patient with bilateral chylothorax after neck lymph node dissection for thyroid cancer were retrospectively analyzed, and the relevant literature was reviewed.
Results: The patient underwent a total thyroidectomy and left neck lymph node dissection, with no evidence of lymph fluid leakage observed during the operation.
Percutaneous nephrolithotripsy (PCNL) is an effective therapeutic approach in cases of lithiasis, which is prone to complications. In this report we present a case of a 52-year-old female patient with recurrent episodes of lithiasis and, after PCNL, evolution with pain and abdominal distension on the 2nd post-operative day due to a perforation of the gallbladder. An exploratory laparotomy was performed, leading to clinical improvement, and the patient was discharged from the hospital on the 7th day after resolving the choleperitoneum.
View Article and Find Full Text PDFParthenolide improves sepsis-induced coagulopathy by inhibiting mitochondrial-mediated apoptosis in vascular endothelial cells through BRD4/BCL-xL pathway.
J Transl Med
January 2025
Department of Anesthesiology, Daping Hospital, Army Medical University, No.10, Changjiang Road, Yuzhong District, Chongqing, 400042, China.
Background: Sepsis is a systemic inflammatory syndrome that can cause coagulation abnormalities, leading to damage in multiple organs. Vascular endothelial cells (VECs) are crucial in the development of sepsis-induced coagulopathy (SIC). The role of Parthenolide (PTL) in regulating SIC by protecting VECs remains unclear.
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