Unlabelled: The paper is aimed at evaluating the frequency of incidence and the thyroiditis type in patients operated on for goiter. In the years 1989-2000, 5149 patients were operated on because of different thyroid disorders. The clinical data of 66 patients with thyroiditis, diagnosed in a post-operating histopathological examination, were subject to a retrospective analysis. There were 64 women and 2 men, aged from 22 to 70, on an average 50.1 years old. There were determined the preoperative diagnosis, the thyroid function--basing upon the levels of TSH and thyroid hormones, the type of operation effected as well as post operative complications. Then, there was also measured the weight of the resected lobes. The prevalent indication for the surgery was non-toxic goiter; instead, toxic goiter was such an indication only in a few cases. In most patients, the thyroid function revealed euthyreosis. The following complications were observed: transient hypocalcemia [two patients], transient paralysis of recurrent laryngeal nerve on one side [one], and wound suppuration [one]. The following types of thyroiditis were found in histopatological examination: Hashimoto (59 patients), Riedl (3 patients), de Quervain (2 patients) and non-specific thyroiditis (2 patients).
Conclusions: 1. Thyroiditis is a rare case in patients operated on for goiter. 2. The most frequent pathological finding is Hasimoto disease.
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JMIR Med Inform
January 2025
Department of Endocrinology and Metabolism, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Background: Many tools have been developed to predict the risk of diabetes in a population without diabetes; however, these tools have shortcomings that include the omission of race, inclusion of variables that are not readily available to patients, and low sensitivity or specificity.
Objective: We aimed to develop and validate an easy, systematic index for predicting diabetes risk in the Asian population.
Methods: We collected the data from the NAGALA (NAfld [nonalcoholic fatty liver disease] in the Gifu Area, Longitudinal Analysis) database.
Antimicrob Resist Infect Control
January 2025
Department of Pediatrics, College of Medicine, The Catholic University of Korea, 222, Banpo-daero, Seocho-gu, Seoul, Republic of Korea.
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Methods: The characteristics of 106 episodes of CRE acquisition (infection or colonization) in 98 patients with severe burns were evaluated by a retrospective medical record review.
BMC Pharmacol Toxicol
January 2025
Department of Pharmacy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Objective: Cyclin-dependent kinase (CDK)-4/6 inhibitors have significantly improved outcomes in several cancers but can also induce various organ system toxicities, including musculoskeletal disorders. This study aimed to comprehensively characterize the musculoskeletal adverse events (MSAEs) associated with CDK4/6 inhibitors based on real-world data.
Methods: Reports of MSAEs linked to CDK4/6 inhibitors from the first quarter (Q1) of 2015 and 2023 Q4 were extracted from the FAERS.
Neurol Res Pract
January 2025
Institute of Clinical Epidemiology and Biometry, Julius-Maximilians-Universität Würzburg (JMU), Haus D7, Josef-Schneider-Straße 2, 97080, Würzburg, Germany.
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Methods: The clinical core data set was developed by a multidisciplinary working group within the German transregional collaborative research network ReTune. The development followed standardized methodology comprising review of available evidence, a consensus process and performance of the first phase of the study.
J Cardiothorac Surg
January 2025
Semmelweis University Heart and Vascular Centre, Budapest, 1122, Hungary.
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