Contribution of Candida albicans ALS1 to the pathogenesis of experimental oropharyngeal candidiasis.

Infect Immun

Biological Research Laboratory, Sankyo Co., Ltd., Shinagawa-ku, Tokyo 140-8710, Japan.

Published: September 2002

We investigated the contribution of Candida albicans ALS1, which encodes a candidal adhesin, to the pathogenesis of experimental murine oropharyngeal candidiasis. Our results indicate that the ALS1 gene product is important for the adherence of the organism to the oral mucosa during the early stage of the infection.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC128218PMC
http://dx.doi.org/10.1128/IAI.70.9.5256-5258.2002DOI Listing

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