When diagnosis of the thyroid carcinoma is made preoperatively, total thyroidectomy with excision of lymph nodes involved in neoplastic process is indicated. The cases of carcinoma diagnosed upon tissue examination after strumectomy performed for other indications should be referred for radical rethyroidectomy. Even after macroscopically total thyroidectomy, postoperative scintigraphy may reveal remnants of thyroid tissue, the most often in the place of pyramidal lobe, in proximity of the laryngeal recurrent nerves or small metastatic lymph nodes overlooked during the first operation. In order to improve the rate of surgical cure, intraoperative scintigraphy was performed. Intraoperative evaluation of totality of the operation was performed in 114 patients. In all cases postoperative scintigraphy revealed iodine uptake above 1% (ranging from 1.9% to 23%). The other group of 186 patients had the radicalness of total thyroidectomy and total rethyroidectomy checked intraoperatively with gamma-beams detector. Radioiodine uptake ranged postoperatively in these patients from 0% to 3.74%. Only 73 (39%) of them required radioiodine treatment due to iodine uptake above the neck. The intraoperative use of gamma-beams detector allows improving totality of thyroidectomy and for significant reduction in number of patients who require ablation with radioiodine.
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Front Endocrinol (Lausanne)
January 2025
Unit of Biostatistics, Epidemiology and Public Health, Department of Cardiac-Thoracic-Vascular Sciences and Public Health, University of Padova, Padua, Italy.
Background: Differentiated thyroid carcinoma is the most common endocrine neoplasm; several studies have shown that individuals perceive the disease as being more severe than it actually is, resulting in a reduced quality of life. The primary aim of this study is to assess the quality of life and perception of illness among patients admitted for radiometabolic therapy, post total thyroidectomy for differentiated thyroid carcinoma. The secondary aim is to identify which patient characteristics are associated with a lower quality of life in order to improve and personalize care.
View Article and Find Full Text PDFPostgrad Med J
January 2025
Institute of Public Health, College of Medicine, National Yang Ming Chiao Tung University, Yang Ming Campus, No. 155, Sec. 2, Linong Street, Beitou District, Taipei 11217, Taiwan.
Background: Thyroid cancer primarily affects young women and raises concerns about future fertility due to treatments of thyroidectomy and radioactive iodine (RAI) therapy. This study investigated the effects of these treatments on pregnancy probability in young female patients post-diagnosis.
Methods: A nationwide, population-based study using data from Taiwan's National Health Insurance Research Database (2000-2017) examined pregnancy likelihood in women ≤45 years with thyroid cancer.
JAMA Otolaryngol Head Neck Surg
January 2025
Department of Otolaryngology-Head & Neck Surgery, South Infirmary Victoria University Hospital, Cork, Ireland.
JAMA Otolaryngol Head Neck Surg
January 2025
Department of General, Visceral, and Endocrine Surgery, Pitié-Salpêtrière Hospital, AP-HP, Paris, France.
Laryngoscope Investig Otolaryngol
February 2025
Objectives: While it is known that surgical costs continue to rise in the United States, there is little information about the specific underlying factors for this variation in many common procedures. This study investigates the influence of geographic location and hospital demographics on hospital cost and postoperative outcomes in adult patients undergoing total thyroidectomy (TT).
Methods: The National Inpatient Sample was queried for patients who underwent primary TT between 2016 and 2017.
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