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Article Synopsis
  • A 40-year-old woman with no prior thyroid issues developed Graves' disease (GD) after undergoing controlled ovarian stimulation (OS) for infertility, despite normal thyroid function tests before the last cycle.
  • Six weeks post-OS, she experienced severe hyperthyroidism with positive anti-thyrotropin receptor antibodies, confirming a GD diagnosis, and started anti-thyroid treatment.
  • Thyroid function remained suboptimal after a year of treatment, leading to a recommendation to postpone further OS cycles until her thyroid condition improved, with possible consideration of surgery if she still wanted to become pregnant.
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Article Synopsis
  • Radiofrequency ablation (RFA) is a safe treatment for benign thyroid nodules, but it carries a risk of injury to the recurrent laryngeal nerve (RLN), which can affect voice function.
  • The study highlights the use of flexible laryngoscopy (FL) to monitor vocal cord (VC) function during RFA, ensuring safety before treating the second nodule in a patient with hyperthyroidism.
  • The findings suggest that using FL is an effective way to minimize RLN injury risk during both single and bilateral RFA treatments, even when the patient is awake.
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Introduction: Hyperthyroidism (HT) has been associated with no insignificant rates of thyroid malignancy. There are no current specific guidelines that suggest routine preoperative imaging for thyroid nodules in patients with Grave's disease. We therefore performed a systematic review assessing rates of thyroid malignancy in patients undergoing surgery for different causes of HT: Grave's disease (GD), toxic adenoma (TA) and toxic multinodular goitre (TMNG).

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Fetal goitrous hypothyroidism is a rare entity and is caused mainly by maternal treatment of Graves' disease (GD). We report a case of a 22-year-old woman referred at 12 weeks of gestation due to hyperthyroidism subsequent to recently diagnosed GD. She started treatment with propylthiouracil and, at 21 weeks of gestation, fetal goitre was detected.

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Epidemiology of hyperthyroidism in Iran: a systematic review and meta-analysis.

J Diabetes Metab Disord

December 2018

1Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.

Background: Hyperthyroidism is a systemic disorder that causes severe morbidity and is even fatal. Several studies have been performed in Iran to determine the epidemiologic properties of hyperthyroidism; however, they did not use a systematic approach or meta-analysis to evaluate the results. Therefore, this systematic review and meta-analysis aimed to evaluate the epidemiologic data on hyperthyroidism in Iran.

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