DiffTool: building, visualizing and querying protein clusters.

Bioinformatics

Laboratoire Génomique des Microorganismes Pathogénes, Institut Pasteur, Département de Biologie Moléculaire, 25 rue du Dr Roux, 75724 Paris Cedex 15, France.

Published: August 2002

Unlabelled: DiffTool is a resource to build and visualize protein clusters computed from a sequence database. The package provides a clustering tool to construct protein families according to sequence similarities and a web interface to query the corresponding clusters. A subtractive genome analysis tool selects protein families specific for a genome or a group of genomes. For each protein cluster, DiffTool includes access to sequences, coloured multiple alignments and phylogenetic trees.

Availability: A cluster database built from yeast and complete prokaryotic genomes is queryable at http://bioweb.pasteur.fr/seqanal/difftool. All the Perl sources are freely available to non-profit organizations upon request.

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Source
http://dx.doi.org/10.1093/bioinformatics/18.8.1143DOI Listing

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