In this article we present data from two sets of experiments designed to investigate how children and adult speakers of English and Kannada (Dravidian) interpret scopally ambiguous sentences containing numerally quantified noun phrases and negation (e.g. Donald didn't find two guys). We use this kind of sentence as a way to find evidence in children's linguistic representations for the hierarchical structure and the abstract relations defined over these structures (in particular, the relation of c-command) that linguists take to be at the core of grammatical knowledge. Specifically, we uncover the existence of systematic differences in the way that children and adult speakers resolve these ambiguities, independent of the language they speak. That is, while adults can easily access either scope interpretation, 4-year-old children display a strong preference for the scopal interpretation of the quantified elements which corresponds to their surface syntactic position. Crucially, however, we show that children's interpretations are constrained by the surface hierarchical relations (i.e. the c-command relations) between these elements and not by their linear order. Children's non-adult interpretations are therefore informative about the nature of the syntactic representations they entertain and the rules they use to determine the meaning of a sentence from its structure.
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http://dx.doi.org/10.1016/s0010-0277(02)00013-6 | DOI Listing |
Cancer Rep (Hoboken)
December 2024
Surgical, Medical and Dental Department of Morphological Sciences Related to Transplant, Oncology and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.
Background: Cancer incidence in the Galapagos archipelago is unknown.
Aim: In 2021, a task force including Ecuadorian and Italian researchers was established to estimate cancer incidence among the 25 244 Galapagos residents.
Methods: Registration covered all malignancies, including malignant melanoma and non-melanoma skin cancers; case recording was based on the International Classification of Diseases for Oncology.
Paediatr Drugs
December 2024
Division of Neurology, Department of Pediatrics, The Hospital for Sick Children, 555 University Avenue, Toronto, ON, M5G 1X8, Canada.
Pediatric-onset multiple sclerosis (POMS) refers to multiple sclerosis with onset before 18 years of age. It is characterized by a more inflammatory course, more frequent clinical relapses, and a greater number of magnetic resonance imaging (MRI) lesions compared with adult-onset MS (AOMS), leading to significant impacts on both disability progression and cognitive outcomes in affected individuals. Managing POMS presents distinct challenges due to the unique needs of pediatric patients and the limited number of disease-modifying therapies (DMTs) approved for pediatric use.
View Article and Find Full Text PDFRheumatol Ther
December 2024
Division of Paediatric Rheumatology and Autoinflammation Reference Centre Tübingen, Department of Paediatrics, University Hospital Tübingen; Member of ERN-RITA, Tübingen, Germany.
Introduction: Interim analysis of the long-term safety and effectiveness of canakinumab, at a patient level, in the mevalonate kinase deficiency/hyperimmunoglobulin-D syndrome (MKD/HIDS) cohort of the RELIANCE registry.
Methods: From June 2018, the RELIANCE registry enrolled paediatric (aged ≥ 2 years) and adult patients (aged ≥ 18 years) with MKD/HIDS who were receiving canakinumab as part of their routine medical care. Safety, physician- and patient-reported measures of disease activity and dosing patterns were evaluated at baseline and every 6 months until end-of-study visit.
PLoS One
December 2024
Department of Women's and Children's Health, Pediatric Neuropsychiatry Unit, Center for Neurodevelopmental Disorders at Karolinska Institutet (KIND), Center for Psychiatry Research Karolinska Institutet, Stockholm, Sweden.
Poor health behaviors have been identified as a critical factor for the burden on healthcare systems and individual suffering. However, comprehensive assessment of health behaviors is time-consuming and often neglected. To address this, we introduce the Lev-screening (Lev-s), a new, brief tool that covers multiple health behaviors.
View Article and Find Full Text PDFInterdiscip Cardiovasc Thorac Surg
December 2024
Division Head, cardiovascular Surgery, Hospital for Sick Children, Toronto, Director of Adult Congenital Heart Surgery, Toronto General Hospital ACHD Unit, and Professor, University of Toronto, Canada.
A_small_ASD_with right-to-left shunt is useful for off-loading a dysfunctional right ventricle postoperatively. However, an ASD with left-to-right shunt may not be as useful for a dysfunctional left ventricle. Experimental data is limited at present.
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