The health of the northern hardwood forest in the southern Appalachian Mountains of Tennessee, North Carolina, and Virginia has gained attention from the media and environmental stakeholders due to a purported decline in forest health at higher elevations. This project examined lead (Pb) and calcium (Ca) concentrations in growth rings of an important northern hardwood species, American beech (Fagus grandifolia Ehrh.) at Mount Rogers and Whitetop Mountain, Virginia and attempted to examine concentration relationships with stem growth patterns. Dominant and codominant trees were sampled from 16 research plots at two elevations. Tree cores were crossdated, divided into sections of 10-yr periods, and analyzed using atomic absorption spectroscopy. Lead concentrations correlated negatively with ring width. Elevation and aspect were significantly associated with the Pb concentration, while Ca concentrations were only associated with aspect. Tree core samples taken from higher elevation plots contained higher Pb concentrations than samples collected from lower elevation plots, while the northwest and southwest aspects contained significantly higher amounts of Pb and Ca. Both Pb and Ca concentrations increased during the 1860s and again during the mid-1900s.
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http://dx.doi.org/10.2134/jeq2002.1137 | DOI Listing |
Environ Monit Assess
December 2024
Environmental Technology Division, CSIR - National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram, Kerala, India, 695019.
The study presents findings from physico-chemical and elemental analyses of fresh faecal matter from a residential apartment in Thiruvananthapuram, Kerala, India. Samples were taken every 8-10 days over 4 months to account for variability and establish baseline data. The study also examines the influence of dietary patterns and toilet cleaners on faecal sludge properties.
View Article and Find Full Text PDFBiol Trace Elem Res
December 2024
School of Public Health, Harbin Medical University, 194 Xuefu Road, Harbin, 150081, Heilongjiang, China.
Autism spectrum disorder (ASD) is a neurodevelopmental disorder emerging during early childhood. However, the mechanism underlying the pathogenesis of ASD remains unclear. This study investigated the alterations of elements in serum and prefrontal cortex of BTBR T + tf/J (BTBR) mice and potential mechanisms.
View Article and Find Full Text PDFJ Biol Chem
December 2024
Department of Pharmacology, Addiction Science, and Toxicology, College of Medicine, The University of Tennessee Health Science Center; Memphis, 38163. Electronic address:
Familial Alzheimer's disease (FAD) is frequently associated with mutations in the amyloid precursor protein (APP), which are thought to lead to cognitive deficits by impairing NMDA receptor (NMDAR)-dependent forms of synaptic plasticity. Given the reliance of synaptic plasticity on NMDAR-mediated Ca entry, shaping of NMDAR activity by APP and/or its disease-causing variants could provide a basis for understanding synaptic plasticity impairments associated with FAD. A region of APP (residues 639-644 within APP695) processed by the γ-secretase complex, which generates amyloid β (Aβ) peptides, is a hotspot for FAD mutations.
View Article and Find Full Text PDFCurr Rheumatol Rep
December 2024
Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, CLS-937, Boston, MA, 02215, USA.
Purpose Of Review: Kidney injury due to lupus nephritis (LN) is a severe and sometimes life-threatening sequela of systemic lupus erythematosus. Autoimmune injury to podocytes has been increasingly demonstrated to be a key driver of LN-related kidney injury because these cells play key roles in glomerular filtration barrier homeostasis. Irreparable podocyte injury impairs these processes and can lead to proteinuria, which is an indicator of poor prognosis in LN.
View Article and Find Full Text PDFJ Pers Med
December 2024
Division of Vascular and Endovascular Surgery, Mayo Clinic, Jacksonville, FL 32224, USA.
Abdominal aortic aneurysm (AAA) is a significant vascular condition characterized by the dilation of the abdominal aorta, presenting a substantial risk of rupture and associated high mortality rates. Current management strategies primarily rely on aneurysm diameter and growth rates to predict rupture risk and determine the timing of surgical intervention. However, this approach has limitations, as ruptures can occur in smaller AAAs below surgical thresholds, and many large AAAs remain stable without intervention.
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