Background: Dermoscopic evaluation of pigmented lesions includes assessment of criteria suggestive of melanocytic proliferation. Dermoscopic diagnosis may be hampered when a nonmelanocytic lesion displays one or more melanocytic features.
Objective: To evaluate the incidence of misleading dermoscopic features characteristic of melanocytic lesions in pigmented seborrheic keratosis (PSK).
Methods: We evaluated 402 clinically typical PSKs from 138 patients with at least one clinically identifiable PSK.
Results: Approximately 10% of PSKs displayed one or more melanocytic features, the most frequent being a "false" pigment network.
Conclusion: The occurrence of a "false" pigment network in PSK can be misleading in the differential diagnosis of clinically equivocal lesions. A correct diagnosis can only be obtained if all available dermoscopic criteria are appropriately assessed together with the clinical examination.
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