Background: Nasal telangiectasia is a common disfiguring condition and may cause significant psychological distress. Although lasers are effective in treating such lesions, there are many disadvantages, such as purpura, scarring, and cost.
Objective: To assess the effectiveness of a combination therapy of CO2 laser and trichloroacetic acid (TCA) for nasal telangiectasia.
Methods: Twenty patients with nasal telangiectasia were treated with CO2 laser 2 weeks after modified sclerotherapy using 80% TCA.
Results: After one treatment session, all patients had excellent results with more than 75% vessel clearance. There were mild side effects, such as transient erythema and fine frosting. After follow-up of 1 year, there were no relapses.
Conclusion: We conclude that CO2 laser after modified sclerotherapy using 80% TCA appears to be a simple, effective, and inexpensive method for the treatment of nasal telangiectasia.
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http://dx.doi.org/10.1046/j.1524-4725.2002.02001.x | DOI Listing |
Photodiagnosis Photodyn Ther
January 2025
Department of Dermatology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University Hangzhou, Zhejiang, 310000, China.. Electronic address:
Rosacea is a chronic, inflammatory dermatological condition primarily affecting the central face, including the cheeks, nose, chin, and forehead[1]. It presents with erythema, phymatous changes, papules, pustules, and telangiectasia. The pathogenesis of rosacea is still unknown.
View Article and Find Full Text PDFAm J Otolaryngol
December 2024
Department of Otolaryngology - Head and Neck Surgery, Washington University School of Medicine, 660 S Euclid Ave, CB 8115, St. Louis, MO 63110, USA; Clinical Outcomes Research Office, Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine, 660 S Euclid Ave, CB 8115, St. Louis, MO 63110, USA. Electronic address:
Background: Hereditary hemorrhagic telangiectasia (HHT) is characterized by abnormal blood vessel formation. One treatment for HHT-related arteriovenous malformations (AVMs) is sclerotherapy, which collapses the blood vessels by irritating the endothelial lining.
Methods: This case series describes two HHT patients undergoing in-office sodium tetradecyl sulfate sclerotherapy for non-nasal telangiectasias and AVMs.
Hereditary Hemorrhagic Telangiectasia (HHT) is an autosomal dominant vascular disorder with manifestations including severe nose bleeding and microhemorrhage in brains. Despite being the second most common inherited bleeding disorder, the pathophysiological mechanism underlying HHT-associated hemorrhage is poorly understood. HHT pathogenesis is thought to follow a Knudsonian two-hit model, requiring a second somatic mutation for lesion formation.
View Article and Find Full Text PDFSemin Pediatr Neurol
December 2024
Department of Pediatrics, University of Pittsburgh Medical Center, Children's Hospital of Pittsburgh, United States. Electronic address:
J Prosthet Dent
November 2024
Consultant Maxillofacial Surgeon, The Department of Maxillofacial, The University Hospitals of Leicester, The Leicester Royal Infirmary, Leicester, United Kingdom.
This clinical report describes the nonsurgical treatment of a patient suffering from severe epistaxis associated with hereditary hemorrhagic telangiectasia (HHT). Unlike the permanent surgical closure of the nostrils, known as the Young procedure, this treatment option provides interim relief from nasal obstruction. It includes the use of cone beam computed tomography (CBCT) and computer-aided design (CAD) to create a patient-specific silicone nasal obturator without the need for an impression of the nasal cavity, thereby preventing irritation to the delicate nasal mucosa that could instigate epistaxis.
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