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J Biomed Inform
January 2025
ITMO University, Saint Petersburg, Russia. Electronic address:
The optimization in the ambulance dispatching process is significant for patients who need early treatments. However, the problem of dynamic ambulance redeployment for destination hospital selection has rarely been investigated. The paper proposes an approach to model and simulate the ambulance dispatching process in multi-agent healthcare environments of large cities.
View Article and Find Full Text PDFAfr J Emerg Med
December 2024
Accident & Emergency Department, The Aga Khan University, Nairobi, Nairobi, Kenya.
Background And Objectives: The Kenya Emergency Medical Care (EMC) Policy 2020-2030 was created to guide the advancement of EMC throughout Kenya. This report describes and maps the ongoing EMC policy development process across Kenya's 47 counties, serving as a real-world example of EMC policy development within a decentralized healthcare system in a low-or middle-income country (LMIC).
Methods: This report evaluates the development of county-specific EMC policies using the Kenya Institute for Public Policy Research and Analysis (KIPPRA) six stages for policy development: 1) problem identification, 2) agenda setting, 3) policy design, 4) approval, 5) implementation, and 6) monitoring and evaluation.
J Interpers Violence
January 2025
University of Alicante, Spain.
Intimate partner sexual violence is a serious problem and difficult to detect, often due to beliefs, myths and gender stereotypes. This study analyzes whether women identify this violence better through direct questions about sexual coercion, using the Semi-structured Interview for the Exploration of Intimate Partner Sexual Violence (EVS), which examines the characteristics and circumstances of these situations. A total of 110 women participated, divided into two groups: 80 who sought help at a center for victims of intimate partner violence and have therefore overcome common barriers to asking for help, and 30 who attended a counseling center during divorce proceedings, without having reported any form of violence.
View Article and Find Full Text PDFJ Comp Eff Res
January 2025
Advanz Pharma, London, UK.
Compared with uncomplicated urinary tract infections (UTIs), complicated UTIs (cUTIs) including acute pyelonephritis (AP) present with significant morbidity, a higher risk of treatment failure and typically require longer courses of treatment, or alternative antibiotics. The emergence of drug-resistant organisms represents a considerable challenge in the treatment of patients with cUTIs/AP and has limited antibiotic options. Carbapenems are considered the current last line of therapy, however, carbapenem resistance represents a growing problem.
View Article and Find Full Text PDFCurr Med Chem
January 2025
Department of Pharmaceutical Biotechnology, Anadolu University, Eskişehir, Turkey.
Introduction: The effectiveness of pharmaceutical treatment methods is vital in cancer treatment. In this context, various targeted drug delivery systems are being developed to minimize or eliminate existing deficiencies and harms. This study aimed to model the interaction of MEN-based drug-targeting systems with cancer cells and determine the properties of interacting MENs.
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