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Molecular profiling of frontal and occipital subcortical white matter hyperintensities in Alzheimer's disease.
Front Neurol
January 2025
Department of Neurology, Massachusetts General Hospital, Charlestown, MA, United States.
White matter hyperintensities (WMHs) are commonly detected on T2-weighted magnetic resonance imaging (MRI) scans, occurring in both typical aging and Alzheimer's disease (AD). Despite their frequent appearance and their association with cognitive decline in AD, the molecular factors contributing to WMHs remain unclear. In this study, we investigated the transcriptomic profiles of two commonly affected brain regions with coincident AD pathology-frontal subcortical white matter (frontal-WM) and occipital subcortical white matter (occipital-WM)-and compared with age-matched cognitively intact controls.
View Article and Find Full Text PDFThe Influence of Depression, Anxiety, and Stress on Ageism Among Undergraduates: Mediating Roles of Life Satisfaction, Gratitude, and Prosociality.
Psychol Res Behav Manag
January 2025
Department of General Education, Jiangxi Youth Vocational College, Nanchang, Jiangxi, People's Republic of China.
Background: The rapid growth of the global aging population highlights the need to address ageism and promote social inclusiveness. While considerable research has explored the impact of perceived ageism on older adults' mental health, limited attention has been given to how negative mental health factors-such as depression, anxiety, and stress (DAS)-influence ageist attitudes among younger populations, along with the psychological mechanisms underlying this relationship.
Purpose: This study first investigates the prevalence of ageism among undergraduates and its variation across certain socio-demographic factors at the research site.
Altered Oscillatory Neural Dynamics Related to Word Prediction in Older Adult Readers.
Lang Cogn Neurosci
July 2024
Beckman Institute for Advanced Science and Technology, University of Illinois Urbana-Champaign, USA.
The engagement of predictive mechanisms during language comprehension can facilitate processing and modulate neural oscillatory activity. These modulations include alpha-band activity decreases prior to expected words, reflecting anticipatory preparation, and frontal theta-band activity following unexpected words, reflecting engagement of cognitive control. It remains unknown how these oscillatory dynamics are impacted by aging.
View Article and Find Full Text PDFHigh prevalence and co-occurrence of modifiable risk factors for non-communicable diseases among university students: a cross-sectional study.
Front Public Health
January 2025
Faculty of Nursing, Department of Medical Nursing, Aydin Adnan Menderes University, Aydin, Türkiye.
Background: Non-communicable diseases (NCDs) are a major global concern. This study aimed to examine the prevalence and co-occurrence of lifestyle risk factors among university students.
Methods: This analytical, cross-sectional study was conducted between January and April 2022.
The Experiences of Healthcare Services and Ageing Among Older Turkish Immigrants: A Qualitative Study.
J Adv Nurs
January 2025
Faculty of Medicine and Health Sciences, Department of Public Health and Nursing, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.
Aims: The aim of this study is to explore patterns of the lived experiences of first-generation Turkish immigrants (≥ 60 years) living and ageing in Norway regarding their experiences with healthcare services and ageing.
Design: This study used a qualitative study.
Methods: The sample consisted of 17 individuals aged 60 and above who were of Turkish origin, and immigrated to and living in Norway.
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