The aim of this study was to clarify whether the pit pattern on the surface of submucosal colorectal carcinoma is associated with level of invasion. We examined the VN pit-pattern (loss or decrease of pits with an amorphous structure) area of the tumor surface in 18 submucosal carcinomas that were classified based on gross appearance as either superficial or broad based sessile polypoid tumors. Pit pattern determination was made according to a previously reported system. We then evaluated the relation between the VN pit-pattern area, the maximum diameter of the VN pit-pattern area obtained stereoscopically after resection, and the depth of submucosal invasion. There was a significant correlation between the area and maximum diameter of the VN pit-pattern segment. There was also significant correlation between the maximum diameter of the VN pit-pattern area and the depth of submucosal invasion. Lesions with a maximum VN pit-pattern area diameter <5 mm showed a depth of submucosal invasion of <1500 microm. In submucosal colorectal carcinoma of the superficial or broad based sessile polypoid type in gross appearance, measurement of the maximum VN pit-pattern area diameter allows estimation of the depth of submucosal invasion.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Imaging colonic polyps in 2024.
Indian J Gastroenterol
October 2024
Department of Gastroenterology, Hepatology and Clinical Nutrition, Aster CMI Hospital, Bengaluru, 560 092, India.
Article Synopsis
- Screening colonoscopy and polypectomy are essential for reducing colorectal cancer rates, especially as India's incidence of colonic polyps and cancer has been increasing despite overall low rates.
- Proper training for healthcare providers in detecting and characterizing polyps is crucial, using techniques like high-definition endoscopy and image-enhanced tools to improve outcomes.
- Advancements in GI endoscopy technology, including artificial intelligence and newer imaging methods, are promising and indicate a need for ongoing education in polyp management and prediction of advanced pathology.
[Risk factors analysis and prediction model construction of submucosal deep infiltration of early colorectal tumor].
Zhonghua Zhong Liu Za Zhi
July 2023
Department of Endoscopy, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
To investigate the risk factors for the development of deep infiltration in early colorectal tumors (ECT) and to construct a prediction model to predict the development of deep infiltration in patients with ECT. The clinicopathological data of ECT patients who underwent endoscopic treatment or surgical treatment at the Cancer Hospital, Chinese Academy of Medical Sciences from August 2010 to December 2020 were retrospectively analyzed. The independent risk factors were analyzed by multifactorial regression analysis, and the prediction models were constructed and validated by nomogram.
View Article and Find Full Text PDFA new subtype of serrated lesions, superficially serrated adenoma (SuSA), has been proposed as a lesion that histopathologically exhibits the morphological features of both conventional adenomas and serrated lesions and is difficult to classify as either one. SuSA has been elucidated to be a precursor lesion of type traditional serrated adenoma. It has also been reported that SuSA may have malignant potential.
View Article and Find Full Text PDFArticle Synopsis
- A "resect-and-discard" strategy for small polyps in the colon is challenging due to difficulty in distinguishing low-grade adenomas from more serious lesions like high-grade adenomas or cancers.
- This study evaluated the use of endocytoscopy (EC) with a specific indicator (normal pit-like structure, or NP-sign) to improve real-time diagnosis of low-grade adenomas compared to traditional imaging methods.
- Results showed that EC with NP-sign significantly outperformed other diagnostic techniques in terms of accuracy and specificity, making it a more reliable option for identifying which lesions can be safely discarded.
Metastasis of Renal Cell Carcinoma to the Stomach Twenty One Years from Initial Diagnosis.
Ulster Med J
May 2022
Consultant Gastroenterologist, Daisy Hill.
A female in her 80's presented to our Emergency Department following a fall. She reported general malaise, weight loss and raised inflammatory markers. Background included renal cell carcinoma 21 years previous, managed with radical nephrectomy.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!