AI Article Synopsis
- - The p10 gene of SINPV is located within a 3.0 kbp fragment and is notable for being the longest p10 gene identified in NPVs, with a coding sequence of 318 nucleotides that translates to a protein of 105 amino acids.
- - The promoter region of the SINPV p10 gene features unique A/TTTGTA motifs and the protein is likely to have a large coiled-coil structure due to the presence of 10 heptad repeats.
- - The genetic organization of the SINPV p10 gene and its nearby open reading frames (ORFs) is collinear with that of SpliNPV, suggesting a close evolutionary relationship between SINPV and SpliNPV,
Article Abstract
The p10 gene was localized within the 3.0 kbp BamH I fragment of the SINPV genome. With a coding sequence of 318 nucleotides, corresponding to a protein of 105 amino acids, the p10 gene of SINPV is the longest p10 gene identified so far in NPVs. The SINPV p10 gene is also distinct in having two A/TTTGTA motifs in the promoter region. With 10 heptad repeats, the SINPV P10 protein is probably forming a relatively large coiled-coil structure. The organization of SINPV ORF552-p10 gene-ORF945 cluster is collinear with that of SpliNPV and their corresponding amino acid sequences of each ORF share high similarity. This indicates that SINPV and SpliNPV belong to a homologous baculovirus group.
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