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Construction and preliminary trial test of a decision-making app for pre-hospital damage control resuscitation.

Chin J Traumatol

February 2025

State Key Laboratory of Trauma, Burn and Combined Injury, Department for Combat Casualty Care Training, Army Medical University, Chongqing, 400038, China.

Purpose: To construct a decision-making app for pre-hospital damage control resuscitation (PHDCR) for severely injured patients, and to make a preliminary trial test on the effectiveness and usability aspects of the constructed app.

Methods: Decision-making algorithms were first established by a thorough literature review, and were then used to be learned by computer with 3 kinds of text segmentation algorithms, i.e.

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Background: Restoration of hand function postextended radial forearm free flap (E-RFFF) is vital but challenging due to complex forearm anatomy and potential complications like reduced range of motion and sensory deficits. Traditional rehabilitation protocols often do not effectively address these issues.

Purpose: This study aims to explore the effectiveness of a hand therapy protocol that incorporates early active motion to enhance recovery outcomes after E-RFFF.

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MARVELD1 inhibits Neuro2a cell migration and tumorigenesis via regulating the transcriptional coactivators and protein methylation.

Bull Cancer

March 2025

Department of Biochemistry and Molecular Biology, College of Basic Medicine, Hebei University of Chinese Medicine, Shijiazhuang, 050200 Hebei Province, China; Hebei Key Laboratory of Chinese Medicine Research on Cardio-cerebrovascular Disease, Shijiazhuang, 050091 Hebei Province, China; Hebei Higher Education Institute Applied Technology Research Center on TCM Development and Industrialization, Shijiazhuang, 050091 Hebei Province, China.

Neuronal cell proliferation and migration play an important regulatory role in the development and tumorigenesis of the nervous system. MARVEL domain-containing protein 1 (MARVELD1) is a potential tumor suppressor gene whose function in nervous system diseases is unclear. This study aimed to analyze the function and molecular mechanism of MARVELD1 gene in Neuro2a cell migration and tumor growth.

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Long noncoding RNAs (lncRNAs) play a crucial role in modulating cancer progression and metastasis. This study investigates the tumor-promoting function of long noncoding RNA BCAR4 in osteosarcoma and elucidates its regulatory mechanism. Although BCAR4 acts as a tumor promoter in osteosarcoma, its regulatory mechanism remains unclear.

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Background: Mycosis fungoides (MF) is the commonest subtype of cutaneous T-cell lymphoma. In the United States, prior studies reported that African Americans (AA) with MF had poor outcomes. Data characterizing differences in racial disparity outcomes over time are limited.

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