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Hepatic adverse events associated with ketamine and esketamine: A population-based disproportionality analysis.
J Affect Disord
January 2025
Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada. Electronic address:
Background And Objective: To determine whether there is disproportionate reporting of hepatobiliary disorders in the United States (US) FDA Adverse Event Reporting System (FAERS) for individuals prescribed ketamine or esketamine.
Design: We identified Medical Dictionary for Regulatory Activities (MedDRA) terms in the FAERS related to hepatobiliary disorders.
Main Measures: Formulations of ketamine and esketamine were evaluated for the proportionality of reporting for each hepatobiliary disorder parameter using the reporting odds ratio (ROR).
Associations Between the Neural Stress Response and Symptoms of Anxiety and Depression.
J Neurosci Res
January 2025
Department of Psychology, University of Regensburg, Regensburg, Germany.
Anxiety and depression disorders show high prevalence rates, and stress is a significant risk factor for both. However, studies investigating the interplay between anxiety, depression, and stress regulation in the brain are scarce. The present manuscript included 124 law students from the LawSTRESS project.
View Article and Find Full Text PDFOn the Measurement of Episodic Empowerment.
Br J Soc Psychol
January 2025
School of Psychology, The University of Adelaide, Adelaide, Australia.
This article reports the development and validation of the Episodic Empowerment Scale (EES): A manipulation check designed to measure a momentary psychological state. In Study 1, participants (n = 125) completed a selection of candidate items after being exposed to a low- or high-power manipulation. Exploratory factor analysis was used to reduce the number of items to a brief five-item measure.
View Article and Find Full Text PDFQuality of life assessment after minimally invasive operative treatment in children with pectus excavatum: A single-center study and literature review.
Adv Clin Exp Med
January 2025
Department of Pediatric Surgery, Antoni Jurasz University Hospital No. 1, Faculty of Medicine, Ludwik Rydygier Medical College in Bydgoszcz, Nicolaus Copernicus University in Toruń, Poland.
Background: Most patients with chest wall deformities have a negative body image, which affects their self-esteem and quality of life (QoL).
Objectives: The aim of this study was to evaluate changes in patients' QoL after minimally invasive repair of pectus excavatum (MIRPE).
Material And Methods: A prospective, single-center study was conducted between 2019 and 2023.
Psychological effects of psychedelics in adolescents.
Front Child Adolesc Psychiatry
June 2024
Centre for Psychedelic Research, Department of Brain Sciences, Faculty of Medicine, Imperial College London, London, United Kingdom.
This study aimed to investigate differences in long-term psychological effects, acute subjective effects, and side effects associated with psychedelic use in adolescents (aged 16-24), compared with adults (aged 25+). Data from two observational online survey cohorts was pooled, involving adolescents (average age 20.4 ± 2.
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