AI Article Synopsis

  • A study comparing children with frontal lobe epilepsy (FLE) and temporal lobe epilepsy (TLE) uncovered differences in their cognitive profiles.
  • Children with FLE showed deficits in executive functions and planning, but their memory skills were largely unaffected.
  • In contrast, children with TLE had memory issues while retaining better executive functioning, indicating distinct patterns of cognitive deficits between the two groups.

Article Abstract

Even though frontal lobe epilepsy (FLE) is a relatively common seizure type, no formal psychometric studies of children with FLE have been reported. We compared 12 children with FLE and 15 children with temporal lobe epilepsy (TLE) on neuropsychological tests of attention, memory, executive functioning, and adaptive functioning. The results of these tests indicated that the children with FLE had deficits in planning and executive functions, whereas their verbal and nonverbal memory was intact. The opposite pattern was observed in children with TLE. Measures of executive functioning and impulse control were the best predictors of adaptive functioning. The findings suggest that children with FLE have a pattern of cognitive deficits that differs markedly from the pattern seen in children with TLE. Children with FLE have prominent deficits in executive functioning that appear to be related to poor behavioral adaptation.

Download full-text PDF

Source
http://dx.doi.org/10.1017/s1355617702801308DOI Listing

Publication Analysis

Top Keywords

children fle
20
lobe epilepsy
12
executive functioning
12
children
9
executive functions
8
temporal lobe
8
adaptive functioning
8
children tle
8
fle
6
executive
5

Similar Publications

Prenatal and Early Childhood Exposure to Proton Pump Inhibitors and Antibiotics and the Risk of Childhood Cancer: A Nationwide Population-Based Cohort Study.

Drug Saf

December 2024

Department of Microbiology, Tumour and Cell Biology (MTC), Centre for Translational Microbiome Research, Karolinska Institutet, Tomtebodavägen 16, Solna, 171 65, Stockholm, Sweden.

Background: Our microbiome is established during infancy, a time important for later health and long-term effects. Proton pump inhibitors and antibiotics are regularly prescribed during pregnancy. Both drugs cause microbiome disturbance and have been associated with increased cancer risk in adults, but effects of these drugs on the growing foetus and infant remain understudied.

View Article and Find Full Text PDF

Executive functions disorders in children with frontal and temporal epilepsy.

Epilepsy Behav

December 2024

Univ Angers, Nantes Université, LPPL, SFR CONFLUENCES, Angers, France; Centre Référent des Troubles d'Apprentissage, Hôpital Femme-Enfant-Adolescent, CHU de Nantes, F-44000 Nantes, France.

Introduction: Children with focal epilepsy often present with executive functions (EFs) deficits. EFs deficits can contribute to adaptive challenges and have a negative impact on academic achievement. The purpose of this study was to investigate the EFs profiles of children diagnosed with frontal lobe epilepsy or temporal lobe epilepsy.

View Article and Find Full Text PDF

Frontal Lobe Epilepsy: Bermuda's Triangle.

Epilepsy Curr

September 2024

Division of Pediatric Neurology and Developmental Medicine, Children's Regional Hospital, Cooper University Health Care, Camden, USA.

Despite great progress in imaging, genetics, surgery, and therapeutics, frontal lobe epilepsy (FLE) continues to be a challenge for neurologists and epileptologists. This manuscript summarizes the latest advancements in FLE discussed at the 2023 Epilepsy Specialist Symposium during the American Epilepsy Society Annual meeting. Correlation between stereoelectroencephalography and clinical symptoms has reinvigorated symptomatology literature in FLE, allowing for more precise aura anatomical localization.

View Article and Find Full Text PDF

Background: Epilepsy is a chronic neurologic disorder characterized by abnormal functioning of brain networks, making it a complex research topic. Recent advancements in neuroimaging technology offer an effective approach to unraveling the intricacies of the human brain. Within different types of epilepsy, there is growing recognition regarding ongoing changes in the default mode network (DMN).

View Article and Find Full Text PDF

Objective: Focal cortical dysplasia (FCD) is the most common pathological cause for pediatric epilepsy, with frontal lobe epilepsy (FLE) being the most prevalent in the pediatric population. We attempted to utilize radiomic and morphological methods on MRI and PET to detect FCD in children with FLE.

Methods: Thirty-seven children with FLE and 20 controls were included in the primary cohort, and a five-fold cross-validation was performed.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!