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The paper presented the results of the combined multistage treatment of 60 patients with advanced carcinoma of the urinary bladder: intra-arterial chemotherapy, immunotherapy, radiation therapy and surgery. Intra-arterial chemotherapy was performed in total dosages of the following drugs: 5-fluorouracil, 3-4 g/m2, adriamycin, 100-120 mg/m2, methotrexate, 20-40 mg/m2, platidiam, 30-50 mg/m2. Immunotherapy was exercised through endolymphatic administration of BCG vaccine in a dose of 0.
View Article and Find Full Text PDFActive specific immunotherapy of renal cell carcinoma patients: a prospective randomized study of hormono-immuno-versus hormonotherapy. Preliminary report of immunological and clinical aspects.
J Biol Response Mod
December 1987
Institute of Oncology, Beilinson Medical Center, Petah-Tiqva, Israel.
Early results of a prospective, randomized trial of active, specific immunotherapy adjunctive to nephrectomy in all stages of RCC are presented. Forty-three patients with median followup of 30 m, who were randomly allocated to either immuno-hormonotherapy arm (IMT), or hormonotherapy alone (HT), are evaluated in terms of progression-free interval (PFI) and overall survival by life table method. Immunotherapy consisted of autologous irradiated tumor cells (AITC), admixed with bacillus Calmette-Guérin (Glaxo) administered by the intradermal and endolymphatic route.
View Article and Find Full Text PDFEndolymphatic isotope and BCG in the management of malignant melanoma.
Aust N Z J Surg
February 1978
Endolymphatic isotope therapy had such promising early clinical results that the M.R.C.
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