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Background: Primary intracranial germ cell tumors (iGCTs) are highly malignant brain tumors that predominantly occur in children and adolescents, with an incidence rate ranking third among primary brain tumors in East Asia (8%-15%). Due to their insidious onset and impact on critical functional areas of the brain, these tumors often result in irreversible abnormalities in growth and development, as well as cognitive and motor impairments in affected children. Therefore, early diagnosis through advanced screening techniques is vital for improving patient outcomes and quality of life.

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Background: Regionally anticoagulated continuous renal replacement therapy with citrate is the first choice for critically ill patients with acute kidney injury. If citrate that reaches the patient exceeds the metabolic capacity, metabolic alkalosis will follow. Bicarbonate from the treatment fluids will also reach the patient and add to the bicarbonate load.

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Sweetpotato Stem Rot Nematode () causes the most devastating disease affecting sweetpotato production in China. The objectives of this study were: i) establish a quantification method using real-time PCR for of sweetpotato; ii) analyze the effect of density at harvest on the percentage of disease incidence in sweetpotatoes; and iii) evaluate the effect of soil physical properties on disease incidence. Populations of isolated from 28 different production areas in Henan Province exhibited identical sequences, and then real-time PCR specific primers (PRNf and PRNr) were designed.

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Transient methods for understanding the properties of strongly oxidizing radicals.

Chem Commun (Camb)

January 2025

Chemistry Division, Brookhaven National Laboratory, Upton, NY 11973-5000, USA.

This review discusses the properties of strongly oxidizing radicals in organic and aqueous media and highlights the challenges in obtaining accurate values of their reduction potentials. Transient redox equilibrium methods based on the use of strong photooxidants or initiated by pulse radiolysis are shown to provide versatile approaches for decoupling electron transfer reactions from follow-up reactivity of unstable radical species, resulting in accurate values of reduction potentials of very positive couples, including some solvent radical cations. We also show that correlations of reduction potentials with Hammett ∑+p parameters, as well as gas phase ionization potentials, can be used to estimate the redox properties of unknown couples within a homologous series of compounds.

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Background: Primary hyperparathyroidism (PHPT) due to a parathyroid adenoma stands as one of the most prevalent endocrinological disorders, with focused parathyroidectomy being the established therapeutic strategy.

Aim: This study aims to investigate whether the volume of the pathological gland influences perioperative outcomes and postoperative morbidity.

Methods: A retrospective analysis was conducted on data from 141 patients who underwent focused parathyroidectomy for PHPT at the University Hospital of Basel between 2007 and 2022.

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