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The goal of this study was to characterize the microbial profile of two different fresh pork cuts, bootjack (BJ) trim and tenderloin (TL), through a 16S rRNA sequencing workflow developed specifically for investigating low-biomass fresh meat within a commercial production schedule. Additionally, this study aimed to determine a baseline prevalence and enumeration profile across these two fresh pork cuts. Results showed that microbiome diversity was different between the BJ and TL, and also differed significantly by processing date.

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Identification of clinical subgroups in anti-SRP positive immune-mediated necrotizing myopathy patients using cluster analysis.

Ther Adv Musculoskelet Dis

January 2025

Department of Rheumatology and Immunology, West China Hospital, Sichuan University, No. 37 Guoxue Alley, Chengdu, 610041, China.

Background: Anti-signal recognition particle immune-mediated necrotizing myopathy (anti-SRP IMNM) is a rare autoimmune disorder characterized by muscle weakness and necrosis. Identifying clinical subgroups within this patient population could facilitate the management of the disease.

Objectives: To identify distinct clinical subgroups of anti-SRP IMNM patients.

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Research establishing factors associated with duration of mechanical ventilation after Tetralogy of Fallot repair, is mainly based on population presenting at early infancy. There are fewer reports regarding repair after infancy, during childhood and preadolescence. To compare two groups of late TOF repair based on post-operative invasive mechanical ventilation duration and explore associations with pre-operative clinical markers of severity of right ventricular outflow tract obstruction.

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Filipinos and Parkinson's disease: A scoping review of the literature.

Parkinsonism Relat Disord

January 2025

The Queen's Medical Center, 1301 Punchbowl Street, Honolulu, HI 96813, USA; University of Hawai'i at Manoa, John A. Burns School of Medicine, 651 Ilalo Street, Honolulu, HI 96813, USA.

Background: Filipinos are the third largest sub-group of Asian Americans in the United States and have greater socioeconomic and health disparities than many other Asian sub-groups [1,2,3,4,5,6,7,8]. Characteristics of Filipino patients with Parkinson's disease (PD) have not been adequately studied.

Objective: To scope the extent, range and nature of current knowledge on PD in Filipino-American (FA) patients in contrast to Filipino patients in general.

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A 49-year-old female presented with the primary complaint of hand tremors. Neurological examination on admission revealed signs of cognitive impairment, bulbar palsy, dystonia, cerebellar ataxia, and pyramidal tract disease. T-weighted brain MRI revealed hyperintense signals in the subcortical white matter, basal ganglia, and cerebellar dentate nucleus, with no atrophy of the brainstem or corpus callosum.

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