Homogeneous irradiation of the entire or a large portion of the superficial scalp poses both technical and dosimetric challenges. Some techniques will irradiate too much of the underlying normal brain while other techniques are either complex and involve field matching problems or may require sophisticated linear accelerator (linac) add-ons such as intensity modulated radiation therapy (IMRT)/electron multileaf collimation. However, many radiotherapy facilities are not equipped with such treatment modalities. We propose a practical treatment technique that can be delivered with a standard linac capable of producing high energy electrons. The proposed technique offers a simple alternative for achieving results equivalent to IMRT. Dose homogeneity throughout the treatment volume is achieved by aiming different energy electron beams at differential areas of the treatment surface to achieve improved dosimetry and rapid treatment delivery, while using a single set-up point. We introduced this treatment technique at our institution to treat superficial cancers of the scalp and other irregular surfaces.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1259/bjr.75.896.750670 | DOI Listing |
Clin Oncol (R Coll Radiol)
January 2025
Department of Radiation Oncology, Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China; Department of Radiotherapy Physics & Technology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
Aims: To assess the robustness of 4D-optimised IMPT and PAT plans against interplay effects in non-small cell lung cancer (NSCLC) patients with respiratory motion over 10 mm, and to provide insights into the use of proton-based stereotactic body radiotherapy (SBRT) for lung cancer with significant tumour movement.
Materials And Methods: Fourteen patients with early-stage NSCLC and tumour motion >10 mm were selected. Three hypofraction regimens were generated using 4D robust optimisation with the IMPT and PAT techniques.
Int J Biol Macromol
January 2025
Department of Chemistry, Faculty of Science, University of Tabuk, Tabuk 71421, Saudi Arabia. Electronic address:
Dyes can seriously harm human health because they linger or break down in the environment and find their way into drinking water through the water cycle. Examples of the most important interactions between MOFs and dyes are provided, and an effort is made to comprehend how surface charge and size compatibility affect the adsorption process. The methods for incorporating functionalized Ce-MOF into electrospun nanofibers made of polyvinyl alcohol and chitosan to create functionalized cerium metal organic framework nanofiber membranes (FCCP nanofiber membranes) are presented in this paper.
View Article and Find Full Text PDFPhys Med
January 2025
Medical Physics Unit, ASST Monza, Monza, Italy.
Purpose: Digital Breast Tomosynthesis (DBT) is an advanced mammography technique for which there are currently no internationally agreed methods and reference values for image quality assessment. The aim of this multicentre study was to evaluate a simple method to assess the technical image quality of reconstructed and synthetic 2D (SM) images of different models of DBT systems using commercially available phantoms.
Methods: The signal difference to noise ratio (SDNR) was chosen as an index of technical image quality and was evaluated for three commercial phantoms, Tomophan, Tormam and CIRS model 015, on 55 DBT systems (six vendors, nine models).
Radiat Environ Biophys
January 2025
Department of Environmental Health Sciences, #820-11, Slot, Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, 4301 W. Markham Str, Little Rock, AR, 72205, USA.
Most studies on the effects of galactic cosmic rays (GCR) have relied on terrestrial irradiation using spatially homogeneous dose distributions of mono-energetic beams comprised of one ion species. Here, we exposed mice to novel beams that more closely mimic GCR, namely, comprising poly-energetic ions of multiple species. Six-month-old male and female C57BL/6J mice were exposed to 0 Gy, 0.
View Article and Find Full Text PDFTechnol Cancer Res Treat
January 2025
Department of Radiation Oncology, Cancer Hospital of Shantou University Medical College, Shantou, Guangdong, PR China.
Purpose: To evaluate the impact of patient setup errors on the dosimetry and radiobiological models of intensity-modulated radiotherapy (IMRT) for esophageal cancer.
Methods And Materials: This retrospective study with 56 patients in thermoplastic mask (TM) and vacuum bag (VB) groups utilized real setup-error (RSE) data from cone-beam CT scans to generate simulated setup-error (SSE) data following a normal distribution. The SSE data were applied to simulate all treatment fractions per patient by shifting the plan isocenter and recalculating the dose.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!