AI Article Synopsis
- The study evaluated and compared patient-controlled sedation (PCS) with physician-administered sedation (PAS) during a specific fertility procedure involving egg retrieval.
- Results showed that while patients experienced more pain with PCS, both methods were considered safe with no significant complications; patient satisfaction remained high for both types, although doctors preferred PAS.
- Ultimately, while PCS may offer less pain relief, it is still a viable option, as many patients preferred it when given a choice.
Article Abstract
Background: This open label study compared the effectiveness of patient-controlled sedation (PCS), with physician-administered sedation (PAS) during transvaginal ultrasound-guided oocyte retrieval (TUGOR).
Methods: A total of 106 patients was randomized using a computer model to receive either PCS (n = 51) or PAS (n = 55). Intra-operative sedation and co-operation were measured on a 5-point scale while severity of pain, and doctor and patient satisfaction were assessed using a 100 mm visual analogue scale. Number of oocytes retrieved and fertilization, cleavage and clinical pregnancy rates were also recorded.
Results: Levels of sedation and co-operation were similar between groups. The pain score was higher in the PCS group during (mean +/- SD, 53 +/- 23 versus 35 +/- 24; P < 0.01) and 2 h after the procedure (29 +/- 27 versus 17 +/- 22; P < 0.05). Doctors were less satisfied with PCS than PAS (62 +/- 25 versus 71 +/- 26; P < 0.05) while patients were highly satisfied with both methods (76 +/- 23 versus 74 +/- 21; not significant). There were no oversedation or peri-operative complications. Fertility outcomes were similar. Patients tended to prefer PCS when given the choice of sedation method.
Conclusion: Although PCS provides less analgesia then PAS during TUGOR, it is safe, satisfactory and accepted by patients.
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| http://dx.doi.org/10.1093/humrep/17.8.2101 | DOI Listing |
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