The case of a 61-year-old woman with Whipple's disease-associated sicca complex is reported. Tropheryma whipplei infection was diagnosed by histological and ultrastructural examination of the jejunal mucosa and sequence analysis of the bacterial 16S ribosomal DNA. The role of vitamin A malabsorption in sicca complex secondary to Whipple's disease is discussed.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC120622PMC
http://dx.doi.org/10.1128/JCM.40.8.3104-3106.2002DOI Listing

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