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Comparative Toxicological Analyses of Traditional Matrices and Blow Fly Larvae in Four Cases of Highly Decomposed Human Cadavers.
Insects
July 2024
Department of Medical Surgical and Health Sciences, University of Trieste, 34127 Trieste, Italy.
In forensic investigation, determining the time and cause of death becomes challenging, especially in cases where the remains are found in advanced decomposition, rendering traditional toxicological samples unavailable or unreliable. Entomotoxicology, an emerging methodology within forensic science, leverages insect specimens collected from cadavers as alternative toxicological samples. Several laboratory and field research studies have highlighted the efficacy in detecting various drugs, toxins, and elements absorbed by insects feeding on cadaveric tissues, even at low concentrations.
View Article and Find Full Text PDFIn the case of extensively putrefied bodies, the analysis of entomological samples may support and complement the toxicological results obtained with other alternative matrices.
Leg Med (Tokyo)
July 2023
CHU Lille, Service de Toxicologie-Génopathies, UF de Toxicologie, Lille 59000, France; University of Lille, ULR 4483-IMPECS-IMPact de l'Environnement Chimique sur la Santé humaine, Lille 59000, France. Electronic address:
Entomotoxicological analysis is not part of routine toxicological analysis. This work aims to present two cases to illustrate the potential of entomological samples as complementary matrices to identify substances in cases of advanced putrefaction. (Case#1) A woman wasexhumed after 14 months to ascertain the exact cause of death.
View Article and Find Full Text PDFUnexpected results found in larvae samples from two postmortem forensic cases.
Forensic Toxicol
January 2022
Institute of Forensic Medicine, University of Munich, Nussbaumstrasse 26, 80336, Munich, Germany.
Purpose: In forensics, entomological specimens can be used as additional/alternative matrices to detect xenobiotics when human specimens are limited in their application. Despite some advantages over implementing putrefied human remains, most medico-legal laboratories do not include entomotoxicological procedures as routine analytical methods. We thus applied two authentic cases to evaluate necrophagous larvae's potential as complementary matrices for toxicological analysis after extensive postmortem decomposition.
View Article and Find Full Text PDFStreptomyces derivatives as an insecticide: Current perspectives, challenges and future research needs for mosquito control.
Acta Trop
May 2022
Higher Institution Centre of Excellence (HICoE), Tropical Infectious Diseases Research and Education Centre (TIDREC), Universiti Malaya, Kuala Lumpur 50603, Malaysia. Electronic address:
The pervasiveness of arboviruses in wreaking havoc on public health has lingered on international health agendas. A scarcity of mosquito-borne disease vaccines and therapies demands prompt attention, as billions of people worldwide are at risk of infections. It is widely known that vector control continues, and in some diseases, remains the only resort in suppressing disease transmissions we presently possess at its disposal.
View Article and Find Full Text PDFToxicological, Enzymatic, and Molecular Assessment of the Insecticide Susceptibility Profile of Triatoma infestans (Hemiptera: Reduviidae, Triatominae) Populations From Rural Communities of Santa Cruz, Bolivia.
J Med Entomol
January 2017
Centro de Investigaciones de Plagas e Insecticidas (UNIDEF, CITEDEF, CONICET, CIPEIN) Juan B. De La Salle 4397 Buenos Aires (B1603ALO), Argentina
A wide range of insecticide resistance profiles has been reported across Bolivian domestic and sylvatic populations of Triatoma infestans (Klug, 1834) (Hemiptera, Reduviidae), including some with levels proven to be a threat for vector control. In this work, the insecticide profile of domestic T. infestans was studied with standardized toxicological bioassays, in an area that has not undergone consistent vector control.
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