Background: There are still open questions about the safety of fragrances.
Objectives: To evaluate the evidence concerning the frequency of contact dermatitis to fragrances in the general population and selected subgroups and the risk factors for sensitization and clinical manifestations.
Methods: Review of published data.
Results: No criteria for a reliable diagnosis of 'contact dermatitis' are available. International recommendations and standardization for patch test methods exist; however, the question whether agents that are positive are causally linked to contact dermatitis remain fraught with uncertainties concerning false-positive rates and clinical relevance. Most of the discussion concerning prevalence or incidence variations of allergic contact dermatitis to fragrances concentrate on the frequency of positive patch tests in clinical series, i.e. 'floating numerators'.
Conclusions: Risk assessment requires that data from different sources are integrated and compared. Both a 'sentinel surveillance' system and more refined epidemiological studies in well-defined populations are needed to reliably assess the risks associated with fragrance exposure.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1159/000063155 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Type I Hypersensitivity due to Basic Blue 99 in a Hair Colour Conditioning Agent.
Contact Dermatitis
January 2025
Department of Dermatology, Tokyo Medical University, Tokyo, Japan.
Phototoxic reaction to oral terbinafine due to Tinea capitis in a child.
Acta Dermatovenerol Croat
November 2024
Prof. Ana Bakija-Konsuo, MD, PhD, Clinic for Dermatovenerology CUTIS, Vukovarska 22, Dubrovnik, Croatia;
We report the case of an 18-month-old boy who developed a phototoxic skin reaction to terbinafine on his scalp, ears, and face in the form of disseminated erythematous plaques, which resembled subacute lupus erythematosus (SCLE) in their clinical presentation. Skin changes appeared a short time after the boy was exposed to sunlight during the period of time when he was treated with oral terbinafine due to Microsporum canis fungal scalp infection. Tinea capitis is a common dermatophyte infection primarily affecting prepubertal children (1).
View Article and Find Full Text PDFBackground Cosmetics have become an integral part of the contemporary lifestyle. Contact dermatitis (CD) is an inflammatory skin disease resulting from exposure to an external chemical present in cosmetics. A patch test is considered the criterion standard method for detecting CD.
View Article and Find Full Text PDFAssessment and Management of Dermatological Issues in Hospitalized Geriatric Patients: A Retrospective Study in a Tertiary Care Hospital.
Cureus
December 2024
Department of Dermatology and Venereology, Ankara Etlik City Hospital, Ankara, TUR.
Background: Skin problems, typically overlooked in elderly patients hospitalized for systemic diseases, can no longer be ignored.
Objectives: This study aimed to investigate the presence and management of dermatological problems in hospitalized elderly patients.
Materials And Methods: This retrospective study involved dermatology consultations for 712 elderly patients (aged ≥ 65 years) hospitalized between October 2022 and October 2023.
The 'MOAHLFA(P) Index': An Attempt to Standardise a Widely Used Array of Descriptors of Patch-Tested Patients.
Contact Dermatitis
January 2025
Clinic of Dermatology, University Hospital and Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
Background: Since its inception in 1980, the MOHL index (% patients who are male, have occupational, hand, or leg dermatitis, respectively) and its later evolutions until the presently used MOAHLFA(P) index (adding % patients with atopic dermatitis, face dermatitis, age 40+ years and positive reaction(s) to ≥ 1 baseline series allergen) have been intended to convey important demographic and clinical information on the patients patch tested in a certain area and time, aiding the interpretation of the observed spectrum of sensitisation.
Objectives: To examine the current usage of the MOAHLFA(P) index and suggest consolidated definitions for its single items.
Methods: A title/abstract search in Medline identified publications mentioning the evolving acronyms.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!