Critical boundaries in the early Drosophila embryo are set by morphogenetic gradients. A new quantitative study shows that the placement of one such boundary is more accurate than the gradient thought to set it. Genetic analysis of the accuracy of the process implicates a gene not previously thought to be involved.
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http://dx.doi.org/10.1016/s0168-9525(02)02724-5 | DOI Listing |
Dermatol Pract Concept
October 2024
Department of Dermatology, Venereology and Leprosy, Andhra Medical College, Visakhapatnam, Andhra Pradesh, India.
Introduction: Dermoscopy is an important noninvasive tool that helps to determine the stability and activity of vitiligo. Various dermoscopic findings help classify the disease as stable or unstable. This is important for the management of the disease, as surgical management requires disease stability.
View Article and Find Full Text PDFClin Ter
November 2024
Department of Clinical and Experimental Medicine, Section of Legal Medicine, University of Foggia, Italy.
Background: In forensics, the term overkill refers to the modus operandi of the offender that goes beyond the immediate need to kill the victim, but not beyond the borders of cruelty. The killer - unable to stop his murderous impulse - seems to want to make sure the victim is dead, repeatedly hitting the corpse. From a forensic point of view, this type of murder is characterized by bloody crime scenes and the discovery of brutal wounds on the victim's body.
View Article and Find Full Text PDFIntern Med J
November 2024
Division of Personalised Oncology, Walter & Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.
Background: Immunotherapy has emerged as a standard treatment for deficient mismatch repair (dMMR) metastatic colorectal cancer (mCRC). Pembrolizumab became widely available as a first-line (1L) option in Australia following the Pharmaceutical Benefits Scheme (PBS) listing in August 2021. The uptake of new treatment options can be lengthy.
View Article and Find Full Text PDFNefrologia (Engl Ed)
November 2024
Unidad de Investigaciónt y Servicio de Nefrología, Hospital Universitario Nuestra Senora de Candelaria, Santa Cruz de Tenerife, Spain. Electronic address:
Cureus
October 2024
Department of Anesthesiology, Uniformed Services University of the Health Sciences, Bethesda, USA.
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