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Role of Adenosine A1 Receptor in Sleep Deprivation-Induced Neuroinflammation: Insights on Rapid Eye Movement Sleep and Fear Extinction Memory Recall in Rats.
Cureus
December 2024
School of Allied Health Sciences, Manav Rachna International Institute of Research and Studies, Faridabad, IND.
Introduction: Sleep deprivation (SD), stemming from a myriad of aetiologies, is a prevalent health condition frequently overlooked. It typically impairs memory consolidation and synaptic plasticity, potentially through neuroinflammatory mechanisms and adenosinergic signalling. It is still unclear whether the adenosine A1 receptor (A1R) modulates SD-induced neurological deficits in the hippocampus.
View Article and Find Full Text PDFA systematic review of the effectiveness of leaded glasses for ensuring safety among healthcare professionals in fluoroscopy.
J Med Imaging Radiat Sci
January 2025
Instituto Politécnico de Coimbra, ESTESC - Coimbra Health School, Medical Imaging and Radiotherapy, Rua 5 de Outubro, S. Martinho do Bispo, Coimbra 3046-854, Portugal. Electronic address:
Background: Currently, there is an increase in procedures across various clinical specialties involving the use of ionising radiation.
Objective: The primary objective of this systematic review is to analyse and compare the existing literature regarding the effectiveness of leaded glasses for healthcare professionals.
Methods: Comprehensive literature searches were conducted for relevant studies published between 2018 and 2023 using the Scopus, PubMed, and Web of Science databases according to preferred reporting items for systematic reviews and meta-analyses (PRISMA) methodology.
Evaluation of (Shared) Autonomy in Robot-Assisted Vitreoretinal Surgery Using a Surgical Model.
Int J Med Robot
February 2025
Department of Mechanical Engineering, The University of Tokyo, Bunkyo, Japan.
Background: Robot-assisted vitreoretinal surgery makes it easier for the surgeons to perform precise and dexterous manipulations required in vitreoretinal procedures.
Methods: We systematically evaluated manual surgery, conventional two-hand teleoperation, a novel one-hand teleoperation, and automation in a needle positioning task using a realistic surgical eye model, measuring the expert surgeon's performances and the novice's learning curves.
Results: The proposed one-hand teleoperation improved the positioning accuracy of expert surgeons , enabled novices to achieve a consistent accuracy more quickly , decreased the novice's workload more quickly , and made it easier for novices to learn to conduct the task quickly .
Exploring Occupational Health Challenges in Pathology: A Cross-Sectional Survey of Indian Pathologists.
Cureus
December 2024
Pathology, BLDE (Deemed to be University) Shri B.M. Patil Medical College, Hospital, and Research Centre, Vijayapura, IND.
Introduction Occupational health hazards are a significant concern for pathologists due to their unique work environment. These professionals face risks from prolonged microscope use, exposure to chemicals such as formalin, and handling sharp instruments, leading to issues such as musculoskeletal disorders and needlestick injuries. Addressing these hazards is crucial for their well-being and the overall efficiency of medical diagnostics.
View Article and Find Full Text PDFAge-related differences in eye blink-related neural activity and functional connectivity during driving.
Heliyon
January 2025
Department of Ergonomics, Leibniz Research Centre for Working Environment and Human Factors, 44139, Dortmund, Germany.
Article Synopsis
- Driving involves complex coordination that deteriorates with age, affecting cognitive and motor functions.
- A study compared blink behavior and neural responses in younger and older adults during reactive and proactive driving tasks, revealing that younger participants had shorter blink durations and more efficient neural processing.
- Functional connectivity analysis indicated that younger adults exhibit stronger network integration in various brain areas, while older adults showed signs of compensatory mechanisms in attention networks, suggesting adaptability in response to cognitive demands.
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