AI Article Synopsis
- Ki-1 positive anaplastic large cell lymphoma (ALCL) is a rare type of aggressive non-Hodgkin's lymphoma with unique characteristics.
- A new case is reported where a patient experienced a relapse of ALCL primarily in the lymph nodes, which presented as widespread skin lesions, including nodules and abnormal redness (erythroderma).
- This situation emphasizes the importance of early biopsy for patients with a history of Ki-1 positive ALCL when new skin symptoms appear.
Article Abstract
Ki-1 (CD30) positive anaplastic large cell lymphoma (ALCL) is an uncommon, high-grade non-Hodgkin's lymphoma with distinct morphologic and immunohistochemical features. Solitary or multiple ulcerated nodules typically characterize cutaneous involvement. Erythroderma is very rare. We report the first case of primary nodal ALCL in which disease relapse manifested as generalized papules, nodules, and erythroderma. This unusual case expands the spectrum of cutaneous disease associated with Ki-1 positive ALCL and highlights the need for early biopsy in patients with a history of Ki-1 positive ALCL who have skin lesions develop.
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| http://dx.doi.org/10.1067/mjd.2002.110668 | DOI Listing |
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