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An investigation of the mechanism of adjacent segment disease in a porcine spine model.
Clin Biomech (Bristol)
January 2025
Department of Kinesiology and Physical Education, Wilfrid Laurier University, Waterloo, Ontario, Canada; Department of Health Sciences, Wilfrid Laurier University, Waterloo, Ontario, Canada. Electronic address:
Background: Fusion changes the biomechanics of the spine leading to the potential development of adjacent segment disease. Despite many studies on adjacent segment disease, it is largely unknown how spinal fixation affects the mechanical properties of the adjacent disc. The purpose of this study was to assess whether axial compression causes mechanical disruption to the annulus when the caudal spinal level is immobilized or injured.
View Article and Find Full Text PDFEffect of a chemically-modified-curcumin on dental resin biodegradation.
Front Oral Health
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Department of General Dentistry, School of Dental Medicine, Stony Brook University, Stony Brook, NY, United States.
Introduction: Previous studies have shown () esterase is a key mediator of dental composite biodegradation, which can contribute to recurrent caries. This study is to investigate the inhibitory effects of a novel Chemically-Modified-Curcumin (CMC 2.24) on esterase activities and related dental material biodegradation.
View Article and Find Full Text PDFOptimizing Tongue Fluid Sampling and Testing Protocols for Enhanced PRRSV Isolation from Perinatal Swine Mortalities.
Viruses
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Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011-3619, USA.
Porcine reproductive and respiratory syndrome virus (PRRSV) remains a major concern for swine health. Isolating PRRSV is essential for identifying infectious viruses and for vaccine formulation. This study evaluated the potential of using tongue fluid (TF) from perinatal piglet mortalities for PRRSV isolation.
View Article and Find Full Text PDFArticle Synopsis
- Atypical porcine pestivirus (APPV), linked to congenital tremor A-II in pigs, was first identified in 2015 and has now been found in various regions globally.
- From 2020 to 2024, a study in Russia screened 2630 pig samples from 14 regions, finding APPV in 12 farms with an overall positive rate of 8.8%, indicating its circulation in Russian swine since at least 2020.
- Phylogenetic analysis of the virus revealed high genetic similarities with Hungarian, USA, and South Korean strains, showing considerable variation among Russian isolates, and confirmed successful replication of one strain in cell culture.
Localization and Molecular Cloning of the Gene for Melatonin Synthesis in Pigs.
Int J Mol Sci
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State Key Laboratory of Animal Biotech Breeding, Key Laboratory of Animal Genetics, Breeding and Reproduction of the Ministry of Agriculture, Frontiers Science Center for Molecular Design Breeding (MOE), College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Melatonin is synthesized in multiple tissues and organs of pigs, and existing studies have shown the presence of the melatonin-synthesizing enzyme ASMT protein. However, the genomic information for the gene has been lacking. The aim of this study was to locate the genomic information of the gene in pigs using comparative genomics analysis and then obtain the coding region information through molecular cloning.
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