Rotary ventricular assist devices (VADs) are primarily used during surgery and short-term postoperative assistance. There are issues involving the use of rotary VADs including the behavior of flow emanating from the assist device which might induce flow irregularities that could potentially lead to stroke or cerebrovascular accident. An in vitro flow visualization study using particle image velocimetry was conducted to evaluate flow fields at the bend of outlet cannulae with angles ranging from 30 degrees to 75 degrees. A multiple disk centrifugal blood pump produced steady, laminar flow fields at the outlet. Flow fields at the bend of each cannula demonstrated the development of a boundary layer along the inner wall and shift of fluid momentum to the outer wall. Stagnant zones along the inner wall were prevalent for each cannula and increased in severity with increasing angle. The outlet flow fields of rotary VADs have the potential to produce thrombus, feasibly leading to thromboembolisms should the bend angle of the outlet cannula be acute enough. Therefore, the placement of the outlet cannula or conduit should be taken into consideration during implantation.
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http://dx.doi.org/10.1046/j.1525-1594.2002.06931_4.x | DOI Listing |
Langmuir
January 2025
CNNFM Lab, School of Mechanical Engineering, College of Engineering, University of Tehran, P.O. Box 11155-4563 Tehran, Iran.
This study investigates the impact of cell dynamics on mixing efficiency within a microfluidic droplet, emphasizing the relationship between cell motion, deformability, and resultant asymmetry in velocity and concentration fields. Simulations were conducted for droplets containing encapsulated cells at varying Peclet numbers ( = 100-800) and coupling constants ( = 0.0025, 0.
View Article and Find Full Text PDFPLoS One
January 2025
School of Civil and Architectural Engineering, Harbin University, Harbin, China.
This work explores an intelligent field irrigation warning system based on the Enhanced Genetic Algorithm-Backpropagation Neural Network (EGA-BPNN) model in the context of smart agriculture. To achieve this, irrigation flow prediction in agricultural fields is chosen as the research topic. Firstly, the BPNN principles are studied, revealing issues such as sensitivity to initial values, susceptibility to local optima, and sample dependency.
View Article and Find Full Text PDFSmall
January 2025
Beijing Key Laboratory for Green Catalysis and Separation and Department of Chemical Engineering, College of Materials Science and Engineering, Beijing University of Technology, Beijing, 100124, P. R. China.
Metal-organic frameworks (MOFs) are rigorously investigated as promising candidates for CO capture and conversion. MOF-on-MOF heterostructures integrate bolstered charger carrier separation with the intrinsic advantages of MOF components, exhibiting immense potential to substantially escalate the efficiency of photocatalytic CO reduction (CORR). However, the structural and compositional complexity poses significant challenges to the controllable development of these heterostructures.
View Article and Find Full Text PDFCochrane Database Syst Rev
January 2025
School of Medical Sciences, Department of Metabolism and Systems Science, WHO Collaborating Centre for Global Women's Health Research, University of Birmingham, Birmingham, UK.
Background: Postpartum haemorrhage (PPH) is the leading cause of maternal mortality worldwide. Accurate diagnosis of PPH can prevent adverse outcomes by enabling early treatment.
Objectives: What is the accuracy of methods (index tests) for diagnosing primary PPH (blood loss ≥ 500 mL in the first 24 hours after birth) and severe primary PPH (blood loss ≥ 1000 mL in the first 24 hours after birth) (target conditions) in women giving birth vaginally (participants) compared to weighed blood loss measurement or other objective measurements of blood loss (reference standards)?
Search Methods: We searched CENTRAL, MEDLINE, Embase, Web of Science Core Collection, ClinicalTrials.
PLoS One
January 2025
Cooperative Innovation Center of Unconventional Oil and Gas, Yangtze University (Ministry of Education & Hubei Province), Wuhan, Hubei, China.
This paper develops a finite element analysis model to investigate the seepage characteristics of cement sheaths, considering the flow properties of their porous medium. The model's applicability under various conditions was evaluated through grid sensitivity tests and model validation, indicating that it effectively captures the seepage behavior of cement sheaths with a reasonable degree of reliability. Key parameters, including cement sheath length, permeability, gap structure, pressure differential, and fluid properties, were analyzed using finite element methods to determine their impact on seepage flow.
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